Intermittent hypoxia with or without hypercapnia is associated with tumorigenesis by decreasing the expression of brain derived neurotrophic factor and miR-34a in rats

Background Very recent studies revealed that obstructive sleep apnoea (OSA) is a contributor of the increased incidence and mortality of cancer in humans,but mechanisms of how OSA promotes tumorigenesis remains largely unknown.We investigated whether intermittent hypoxia with and without hypercapnia...

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Veröffentlicht in:Chinese medical journal 2014, Vol.127 (1), p.43-47
Hauptverfasser: Zhang, Jing, Guo, Xu, Shi, Yanwei, Ma, Jing, Wang, Guangfa
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Sprache:eng
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