Molecular mechanism of icariin on rat asthmatic model

Background Effects of icariin on airway inflammation in asthmatic rats and the intervention of LPS induced inflammation are interfered with the machanism of icariin. Our study aimed to observe the effect of icariin on ovalbumin-induced imbalance of Th1/Th2 cytokine expression and its mechanism. Meth...

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Veröffentlicht in:	Chinese medical journal 2011-09, Vol.124 (18), p.2899-2906
Hauptverfasser:	Xu, Chang-Qing, LE, Jing-Jing, Duan, Xiao-Hong, DU, Wei-Jing, Liu, Bao-Jun, Wu, Jing-Feng, Cao, Yu-Xue, Dong, Jing-Cheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma - drug therapy Asthma - immunology Asthma - metabolism Blotting, Western Disease Models, Animal Enzyme-Linked Immunosorbent Assay Flavonoids - therapeutic use GATA3 Transcription Factor - metabolism Immunohistochemistry Interferon-gamma - metabolism Interleukin-4 - metabolism Lung - metabolism Male mRNA表达 Ovalbumin - metabolism Polymerase Chain Reaction Rats Rats, Sprague-Dawley SD大鼠 T-Box Domain Proteins - metabolism Th1 Cells - drug effects Th1 Cells - metabolism Th2 Cells - drug effects Th2 Cells - metabolism Transcription Factor RelA - metabolism Western印迹法免疫组化染色分子机制哮喘模型组淫羊藿苷
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