Effect of probucol on vascular remodeling due to atherosclerosis in rabbits： an intravascular ultrasound study

Background Probucol is known to reduce the development of atherosclerotic lesions, but its impact on vascular remodeling associated with de novo atherosclerosis is incompletely understood. We therefore examined the effect of probucol on vascular remodeling in a rabbit model of established atheroscle...

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Veröffentlicht in:	Chinese medical journal 2011-06, Vol.124 (12), p.1840-1847
Hauptverfasser:	Li, Ting-Ting, Xie, Yi, Guo, Yuan, Tian, Hong-Bo, Zhang, Jian-Ning, Peng, Jie, Zhang, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - pharmacology Aorta - pathology Apoptosis - drug effects Atherosclerosis - drug therapy Atherosclerosis - metabolism Atherosclerosis - pathology Lipids - blood Macrophages - drug effects Macrophages - physiology Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Oxidative Stress Probucol - pharmacology Rabbits Ultrasonography, Interventional - methods 免疫组织化学动脉粥样硬化基质金属蛋白酶-2 家兔普罗布考管内血管重塑超声
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