1,25-Dihydroxyvitamin D3 pretreatment enhances the efficacy of allergen immunotherapy in a mouse allergic asthma model

Background Allergen-specific immunotherapy can induce immune tolerance to specific allergens by regulating immune status of individuals. However, its clinical application is limited due to individual differences in efficacy among patients and un-confirmed safety. 1,25 Dihydroxyvitamin D3 （1,25（OH）2D...

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Veröffentlicht in:	Chinese medical journal 2010-12, Vol.123 (24), p.3591-3596
Hauptverfasser:	Ma, Jian-Xin, Xia, Jun-Bo, Cheng, Xiao-Ming, Wang, Chang-Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma - immunology Asthma - pathology Asthma - therapy Bronchoalveolar Lavage Fluid - immunology Calcitriol - therapeutic use Cytokines - analysis Desensitization, Immunologic Disease Models, Animal Female Immunoglobulin E - blood Mice Mice, Inbred BALB C Ovalbumin - immunology 免疫治疗免疫球蛋白E 维生素D3 过敏原过敏性哮喘预处理
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