Role of PI3K/Akt signaling in the protective effect of magnesium sulfate against ischemia-perfusion injury of small intestine in rats

Background The protective effects of magnesium sulfate against ischemia-reperfusion injury of the small intestine in Sprague-Dawley （SD） rats have been confirmed in our previous research. However, its exact mechanism is unclear. This study was to evaluate the role of PI3K/Akt signal pathway in the p...

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Veröffentlicht in:	Chinese medical journal 2010-06, Vol.123 (11), p.1447-1452
Hauptverfasser:	Chen, Shi-da, Chen, Ya-bin, Peng, You, Xu, Jia, Chen, Su-shan, Zhang, Jun-long, Li, Zheng-zhang, Tan, Zhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amine Oxidase (Copper-Containing) - metabolism Animals Apoptosis - drug effects Blotting, Western Disease Models, Animal Intestinal Mucosa - cytology Intestinal Mucosa - drug effects Intestine, Small - drug effects Magnesium Sulfate - therapeutic use Malondialdehyde - metabolism Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Sprague-Dawley Reperfusion Injury - prevention & control Signal Transduction - drug effects
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