Changes of sphingolipids profiles after ischemia-reperfusion injury in the rat liver

Background Hepatic ischemia-reperfusion （I/R） injury occurs in many clinical procedures. The molecular mechanisms responsible for hepatic I/R injury however remain unknown. Sphingolipids, in particular ceramide, play a role in stress and death receptor-induced hepatocellular death, contributing to t...

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Veröffentlicht in:	Chinese medical journal 2009-12, Vol.122 (24), p.3025-3031
Hauptverfasser:	Zhai, Shu-Ting, Liu, Guang-Yi, Xue, Fei, Sun, Gong-Ping, Liang, Liang, Chen, Wei, Xu, Guo-Dong, Li, Jun-Jian, Yang, Jun, Liang, Ting-Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Liver - metabolism Liver - pathology Male Rats Rats, Sprague-Dawley Reperfusion Injury - metabolism Reverse Transcriptase Polymerase Chain Reaction Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sphingolipids - metabolism Tumor Necrosis Factor-alpha - genetics 个人资料分子机制大鼠模型激光解吸电离神经酰胺缺血再灌注肝损伤肝脏疾病
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