Continuous epidural block of the cervical vertebrae for cervicogenic headache
Background Cervicogenic headache (CEH) is caused by a structural abnormality in the cervical spine. Available treatments for CEH include medical therapy, local botulinum toxin injection, cervical epidural corticosteroid injection, and surgery. The objective of this study was to investigate the safet...
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description | Background Cervicogenic headache (CEH) is caused by a structural abnormality in the cervical spine. Available treatments for CEH include medical therapy, local botulinum toxin injection, cervical epidural corticosteroid injection, and surgery. The objective of this study was to investigate the safety and efficacy of a continuous epidural block of the cervical vertebra.
Methods Medical records were retrospectively analyzed for 37 patients diagnosed with CEH treated by a continuous epidural block of the cervical vertebra with lidocaine, dexamethasone, and saline (5 ml/min) for 3-4 weeks and triamcinolone acetonide 5 mg once weekly for 3-4 weeks. Pain was measured via the visual analogue scale (VAS) in combination with quality of life assessment. Outcome measures were patient-reported days with mild or moderate pain, occurrence of severe pain, and the daily oral dosages of non-steroidal anti-inflammatory drug use (NSAID).
Results In the 3 months immediately preceding placement of the epidural catheter, the mean number of days with mild or moderate pain was 22.0±4.3. The mean occurrence of severe pain was (3.20±0.75) times and the mean oral dosage of NSAID was (1267±325) mg. During the first 6 months after epidural administration of lidocaine and corticosteroids, the mean number of days with mild or moderate pain, the mean occurrence of severe pain, and the mean daily oral dosages of NSAIDs were significantly decreased compared to 3-month period immediately preceding treatment (P 〈0.01). By 12 months post-treatment, no significant difference in these three outcome measures was noted.
Conclusions Continuous epidural block of the cervical vertebra for patients with CEH is effective for at least six months. Further research is needed to elucidate mechanisms of action and to prolong this effect. |
doi_str_mv | 10.3760/cma.j.issn.0366-6999.2009.04.0013 |
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Methods Medical records were retrospectively analyzed for 37 patients diagnosed with CEH treated by a continuous epidural block of the cervical vertebra with lidocaine, dexamethasone, and saline (5 ml/min) for 3-4 weeks and triamcinolone acetonide 5 mg once weekly for 3-4 weeks. Pain was measured via the visual analogue scale (VAS) in combination with quality of life assessment. Outcome measures were patient-reported days with mild or moderate pain, occurrence of severe pain, and the daily oral dosages of non-steroidal anti-inflammatory drug use (NSAID).
Results In the 3 months immediately preceding placement of the epidural catheter, the mean number of days with mild or moderate pain was 22.0±4.3. The mean occurrence of severe pain was (3.20±0.75) times and the mean oral dosage of NSAID was (1267±325) mg. During the first 6 months after epidural administration of lidocaine and corticosteroids, the mean number of days with mild or moderate pain, the mean occurrence of severe pain, and the mean daily oral dosages of NSAIDs were significantly decreased compared to 3-month period immediately preceding treatment (P 〈0.01). By 12 months post-treatment, no significant difference in these three outcome measures was noted.
Conclusions Continuous epidural block of the cervical vertebra for patients with CEH is effective for at least six months. Further research is needed to elucidate mechanisms of action and to prolong this effect.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>DOI: 10.3760/cma.j.issn.0366-6999.2009.04.0013</identifier><identifier>PMID: 19302749</identifier><language>eng</language><publisher>China: Department of Pain, Xuanwu Hospital, Capital Medical University, Beijing 100053, China</publisher><subject>Adult ; Aged ; Anesthesia, Epidural - methods ; Cervical Vertebrae ; Dexamethasone - therapeutic use ; Female ; Humans ; Lidocaine - therapeutic use ; Male ; Middle Aged ; Pain - drug therapy ; Pain - pathology ; Post-Traumatic Headache - drug therapy ; Post-Traumatic Headache - pathology ; Retrospective Studies ; Treatment Outcome ; Triamcinolone Acetonide - therapeutic use ; 硬膜外皮质类固醇注射 ; 细胞治疗 ; 药物治疗 ; 连续硬膜外阻滞 ; 非甾体抗炎药 ; 非类固醇消炎药 ; 颈源性头痛</subject><ispartof>Chinese medical journal, 2009-02, Vol.122 (4), p.427-430</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-5fa4503664587c2b236a322896ff78abd1149771196e80faa0ff1c1656884dcc3</citedby><cites>FETCH-LOGICAL-c448t-5fa4503664587c2b236a322896ff78abd1149771196e80faa0ff1c1656884dcc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>315,781,785,865,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19302749$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>He, Ming-wei</creatorcontrib><creatorcontrib>Ni, Jia-xiang</creatorcontrib><creatorcontrib>Guo, Yu-na</creatorcontrib><creatorcontrib>Wang, Qi</creatorcontrib><creatorcontrib>Yang, Li-qiang</creatorcontrib><creatorcontrib>Liu, Jing-jie</creatorcontrib><title>Continuous epidural block of the cervical vertebrae for cervicogenic headache</title><title>Chinese medical journal</title><addtitle>Chinese Medical Journal</addtitle><description>Background Cervicogenic headache (CEH) is caused by a structural abnormality in the cervical spine. Available treatments for CEH include medical therapy, local botulinum toxin injection, cervical epidural corticosteroid injection, and surgery. The objective of this study was to investigate the safety and efficacy of a continuous epidural block of the cervical vertebra.
Methods Medical records were retrospectively analyzed for 37 patients diagnosed with CEH treated by a continuous epidural block of the cervical vertebra with lidocaine, dexamethasone, and saline (5 ml/min) for 3-4 weeks and triamcinolone acetonide 5 mg once weekly for 3-4 weeks. Pain was measured via the visual analogue scale (VAS) in combination with quality of life assessment. Outcome measures were patient-reported days with mild or moderate pain, occurrence of severe pain, and the daily oral dosages of non-steroidal anti-inflammatory drug use (NSAID).
Results In the 3 months immediately preceding placement of the epidural catheter, the mean number of days with mild or moderate pain was 22.0±4.3. The mean occurrence of severe pain was (3.20±0.75) times and the mean oral dosage of NSAID was (1267±325) mg. During the first 6 months after epidural administration of lidocaine and corticosteroids, the mean number of days with mild or moderate pain, the mean occurrence of severe pain, and the mean daily oral dosages of NSAIDs were significantly decreased compared to 3-month period immediately preceding treatment (P 〈0.01). By 12 months post-treatment, no significant difference in these three outcome measures was noted.
Conclusions Continuous epidural block of the cervical vertebra for patients with CEH is effective for at least six months. Further research is needed to elucidate mechanisms of action and to prolong this effect.</description><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia, Epidural - methods</subject><subject>Cervical Vertebrae</subject><subject>Dexamethasone - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Lidocaine - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pain - drug therapy</subject><subject>Pain - pathology</subject><subject>Post-Traumatic Headache - drug therapy</subject><subject>Post-Traumatic Headache - pathology</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Triamcinolone Acetonide - therapeutic use</subject><subject>硬膜外皮质类固醇注射</subject><subject>细胞治疗</subject><subject>药物治疗</subject><subject>连续硬膜外阻滞</subject><subject>非甾体抗炎药</subject><subject>非类固醇消炎药</subject><subject>颈源性头痛</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMFu1DAQhi0EotvCK6CIAxKHhLFjO_GxWgFFKuICZ8tx7I3TxN7aSRE8PY42oqeRRr_m--dD6COGqm44fNKzqsbKpeQrqDkvuRCiIgCiAloB4PoFOhBGSck4xS_R4X_oCl2nNAIQxhr-Gl1hUQNpqDig78fgF-fXsKbCnF2_RjUV3RT0QxFssQym0CY-OZ23TyYupovKFDbEfR1OxjtdDEb1Sg_mDXpl1ZTM233eoF9fPv883pX3P75-O97el5rSdimZVZRt5ShrG006UnNVE9IKbm3Tqq7HmIqmwVhw04JVCqzFGnPG25b2Wtc36MPl7m_lrfInOYY1-kyUfwc9j5sSoNnHc_Acw-Nq0iJnl7SZJuVNflnyBhjO-By8vQR1DClFY-U5ulnFPxKD3OTLLF-OcpMvt-py8yo3kgQq4QJ7t8PWbjb984Xddg683yFD8KdHl4t3Sj9YNxlJBOctBl7_A6JYjtA</recordid><startdate>20090220</startdate><enddate>20090220</enddate><creator>He, Ming-wei</creator><creator>Ni, Jia-xiang</creator><creator>Guo, Yu-na</creator><creator>Wang, Qi</creator><creator>Yang, Li-qiang</creator><creator>Liu, Jing-jie</creator><general>Department of Pain, Xuanwu Hospital, Capital Medical University, Beijing 100053, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20090220</creationdate><title>Continuous epidural block of the cervical vertebrae for cervicogenic headache</title><author>He, Ming-wei ; Ni, Jia-xiang ; Guo, Yu-na ; Wang, Qi ; Yang, Li-qiang ; Liu, Jing-jie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-5fa4503664587c2b236a322896ff78abd1149771196e80faa0ff1c1656884dcc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anesthesia, Epidural - methods</topic><topic>Cervical Vertebrae</topic><topic>Dexamethasone - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Lidocaine - therapeutic use</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pain - drug therapy</topic><topic>Pain - pathology</topic><topic>Post-Traumatic Headache - drug therapy</topic><topic>Post-Traumatic Headache - pathology</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Triamcinolone Acetonide - therapeutic use</topic><topic>硬膜外皮质类固醇注射</topic><topic>细胞治疗</topic><topic>药物治疗</topic><topic>连续硬膜外阻滞</topic><topic>非甾体抗炎药</topic><topic>非类固醇消炎药</topic><topic>颈源性头痛</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>He, Ming-wei</creatorcontrib><creatorcontrib>Ni, Jia-xiang</creatorcontrib><creatorcontrib>Guo, Yu-na</creatorcontrib><creatorcontrib>Wang, Qi</creatorcontrib><creatorcontrib>Yang, Li-qiang</creatorcontrib><creatorcontrib>Liu, Jing-jie</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>He, Ming-wei</au><au>Ni, Jia-xiang</au><au>Guo, Yu-na</au><au>Wang, Qi</au><au>Yang, Li-qiang</au><au>Liu, Jing-jie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Continuous epidural block of the cervical vertebrae for cervicogenic headache</atitle><jtitle>Chinese medical journal</jtitle><addtitle>Chinese Medical Journal</addtitle><date>2009-02-20</date><risdate>2009</risdate><volume>122</volume><issue>4</issue><spage>427</spage><epage>430</epage><pages>427-430</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><abstract>Background Cervicogenic headache (CEH) is caused by a structural abnormality in the cervical spine. Available treatments for CEH include medical therapy, local botulinum toxin injection, cervical epidural corticosteroid injection, and surgery. The objective of this study was to investigate the safety and efficacy of a continuous epidural block of the cervical vertebra.
Methods Medical records were retrospectively analyzed for 37 patients diagnosed with CEH treated by a continuous epidural block of the cervical vertebra with lidocaine, dexamethasone, and saline (5 ml/min) for 3-4 weeks and triamcinolone acetonide 5 mg once weekly for 3-4 weeks. Pain was measured via the visual analogue scale (VAS) in combination with quality of life assessment. Outcome measures were patient-reported days with mild or moderate pain, occurrence of severe pain, and the daily oral dosages of non-steroidal anti-inflammatory drug use (NSAID).
Results In the 3 months immediately preceding placement of the epidural catheter, the mean number of days with mild or moderate pain was 22.0±4.3. The mean occurrence of severe pain was (3.20±0.75) times and the mean oral dosage of NSAID was (1267±325) mg. During the first 6 months after epidural administration of lidocaine and corticosteroids, the mean number of days with mild or moderate pain, the mean occurrence of severe pain, and the mean daily oral dosages of NSAIDs were significantly decreased compared to 3-month period immediately preceding treatment (P 〈0.01). By 12 months post-treatment, no significant difference in these three outcome measures was noted.
Conclusions Continuous epidural block of the cervical vertebra for patients with CEH is effective for at least six months. Further research is needed to elucidate mechanisms of action and to prolong this effect.</abstract><cop>China</cop><pub>Department of Pain, Xuanwu Hospital, Capital Medical University, Beijing 100053, China</pub><pmid>19302749</pmid><doi>10.3760/cma.j.issn.0366-6999.2009.04.0013</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Anesthesia, Epidural - methods Cervical Vertebrae Dexamethasone - therapeutic use Female Humans Lidocaine - therapeutic use Male Middle Aged Pain - drug therapy Pain - pathology Post-Traumatic Headache - drug therapy Post-Traumatic Headache - pathology Retrospective Studies Treatment Outcome Triamcinolone Acetonide - therapeutic use 硬膜外皮质类固醇注射 细胞治疗 药物治疗 连续硬膜外阻滞 非甾体抗炎药 非类固醇消炎药 颈源性头痛 |
title | Continuous epidural block of the cervical vertebrae for cervicogenic headache |
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