Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome
Most cases of acute coronary syndrome (ACS) involve coronary atherosclerosis and plaque rupture, as well as subsequent thrombosis. The initial thrombotic events leading to red thrombus formation are platelet adherence and aggregation. Platelets play a very important role during the establishment and...
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Veröffentlicht in: | Chinese medical journal 2008-05, Vol.121 (9), p.850-852 |
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creator | Ren, Yi-hong Yang, Ting-shu Wang, Yu Gai, Lu-yue Liu, Hong-bin Chen, Lian Wang, Hong-ye Wang, Chun-ya Xu, Xiu-li Jin, Jing Xin, You-hong Li, Rong-bin Li, Hai-yan Lin, Lin Liu, Chun-xue |
description | Most cases of acute coronary syndrome (ACS) involve coronary atherosclerosis and plaque rupture, as well as subsequent thrombosis. The initial thrombotic events leading to red thrombus formation are platelet adherence and aggregation. Platelets play a very important role during the establishment and progression of a thrombosis in a coronary artery. Therefore, in recent years guidelines have been developed in an effort to strengthen antiplatelet therapy in ACS, but unfortunately the methods to evaluate platelet activity and the strength of platelet inhibition are lacking. |
doi_str_mv | 10.1097/00029330-200805010-00018 |
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The initial thrombotic events leading to red thrombus formation are platelet adherence and aggregation. Platelets play a very important role during the establishment and progression of a thrombosis in a coronary artery. Therefore, in recent years guidelines have been developed in an effort to strengthen antiplatelet therapy in ACS, but unfortunately the methods to evaluate platelet activity and the strength of platelet inhibition are lacking.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>DOI: 10.1097/00029330-200805010-00018</identifier><identifier>PMID: 18701053</identifier><language>eng</language><publisher>China: Department of Cardiology, General Hospital of the Chinese People's Liberation Army, Beijing 100083, China</publisher><subject><![CDATA[Acute Coronary Syndrome - drug therapy ; Angioplasty, Balloon, Coronary ; Aspirin - administration & dosage ; Humans ; Platelet Aggregation Inhibitors - administration & dosage ; Thrombelastography ; Ticlopidine - administration & dosage ; Ticlopidine - analogs & derivatives ; Tyrosine - administration & dosage ; Tyrosine - analogs & derivatives ; 急性冠状动脉血栓症 ; 血小板]]></subject><ispartof>Chinese medical journal, 2008-05, Vol.121 (9), p.850-852</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18701053$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ren, Yi-hong</creatorcontrib><creatorcontrib>Yang, Ting-shu</creatorcontrib><creatorcontrib>Wang, Yu</creatorcontrib><creatorcontrib>Gai, Lu-yue</creatorcontrib><creatorcontrib>Liu, Hong-bin</creatorcontrib><creatorcontrib>Chen, Lian</creatorcontrib><creatorcontrib>Wang, Hong-ye</creatorcontrib><creatorcontrib>Wang, Chun-ya</creatorcontrib><creatorcontrib>Xu, Xiu-li</creatorcontrib><creatorcontrib>Jin, Jing</creatorcontrib><creatorcontrib>Xin, You-hong</creatorcontrib><creatorcontrib>Li, Rong-bin</creatorcontrib><creatorcontrib>Li, Hai-yan</creatorcontrib><creatorcontrib>Lin, Lin</creatorcontrib><creatorcontrib>Liu, Chun-xue</creatorcontrib><title>Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome</title><title>Chinese medical journal</title><addtitle>Chinese Medical Journal</addtitle><description>Most cases of acute coronary syndrome (ACS) involve coronary atherosclerosis and plaque rupture, as well as subsequent thrombosis. The initial thrombotic events leading to red thrombus formation are platelet adherence and aggregation. Platelets play a very important role during the establishment and progression of a thrombosis in a coronary artery. Therefore, in recent years guidelines have been developed in an effort to strengthen antiplatelet therapy in ACS, but unfortunately the methods to evaluate platelet activity and the strength of platelet inhibition are lacking.</description><subject>Acute Coronary Syndrome - drug therapy</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Aspirin - administration & dosage</subject><subject>Humans</subject><subject>Platelet Aggregation Inhibitors - administration & dosage</subject><subject>Thrombelastography</subject><subject>Ticlopidine - administration & dosage</subject><subject>Ticlopidine - analogs & derivatives</subject><subject>Tyrosine - administration & dosage</subject><subject>Tyrosine - analogs & derivatives</subject><subject>急性冠状动脉血栓症</subject><subject>血小板</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkc1u1TAQhS0EoreFV0AWC3YB_8ROvERVaZEqsSnraOw4N744dmo7VOnTY2iRuhpp5jszOmcQwpR8pkR1XwghTHFOGkZITwShpKkt2r9CByZa1gjZ0tfoQLiUjVRKnaHznE9VJEQn36Iz2ndVI_gBpavf4DcoLgYcJ1ySW73FEIprVg_FeltwmW2Cdcd6x0sc3eTsWHspLtp6yCUe63TesQt4rYtsKBk_uDJjMFux2MQUA6Qd5z2MVWTfoTcT-GzfP9cL9PPb1d3lTXP74_r75dfbxjDZlWYExoRRdJS8Omxhagk3oxJyMqPptOG0Y8CNUNr0QKzVymqttIKWtaKXgl-gT097HyBMEI7DKW4p1IvD42yW07_oFKEvwDXF-83mMiwuG-s9BBu3PEjVshriX_DDM7jpxY7DmtxSnQ3_46zAxyfAzDEc7109qsH8mpy3A-toX__R8z-qXoaZ</recordid><startdate>20080505</startdate><enddate>20080505</enddate><creator>Ren, Yi-hong</creator><creator>Yang, Ting-shu</creator><creator>Wang, Yu</creator><creator>Gai, Lu-yue</creator><creator>Liu, Hong-bin</creator><creator>Chen, Lian</creator><creator>Wang, Hong-ye</creator><creator>Wang, Chun-ya</creator><creator>Xu, Xiu-li</creator><creator>Jin, Jing</creator><creator>Xin, You-hong</creator><creator>Li, Rong-bin</creator><creator>Li, Hai-yan</creator><creator>Lin, Lin</creator><creator>Liu, Chun-xue</creator><general>Department of Cardiology, General Hospital of the Chinese People's Liberation Army, Beijing 100083, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20080505</creationdate><title>Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome</title><author>Ren, Yi-hong ; Yang, Ting-shu ; Wang, Yu ; Gai, Lu-yue ; Liu, Hong-bin ; Chen, Lian ; Wang, Hong-ye ; Wang, Chun-ya ; Xu, Xiu-li ; Jin, Jing ; Xin, You-hong ; Li, Rong-bin ; Li, Hai-yan ; Lin, Lin ; Liu, Chun-xue</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c267t-da225c91d630504af403cd956fcdc7bc3172a3c59bc8a0eeb9ebb9b9a42458653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Acute Coronary Syndrome - drug therapy</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Aspirin - administration & dosage</topic><topic>Humans</topic><topic>Platelet Aggregation Inhibitors - administration & dosage</topic><topic>Thrombelastography</topic><topic>Ticlopidine - administration & dosage</topic><topic>Ticlopidine - analogs & derivatives</topic><topic>Tyrosine - administration & dosage</topic><topic>Tyrosine - analogs & derivatives</topic><topic>急性冠状动脉血栓症</topic><topic>血小板</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ren, Yi-hong</creatorcontrib><creatorcontrib>Yang, Ting-shu</creatorcontrib><creatorcontrib>Wang, Yu</creatorcontrib><creatorcontrib>Gai, Lu-yue</creatorcontrib><creatorcontrib>Liu, Hong-bin</creatorcontrib><creatorcontrib>Chen, Lian</creatorcontrib><creatorcontrib>Wang, Hong-ye</creatorcontrib><creatorcontrib>Wang, Chun-ya</creatorcontrib><creatorcontrib>Xu, Xiu-li</creatorcontrib><creatorcontrib>Jin, Jing</creatorcontrib><creatorcontrib>Xin, You-hong</creatorcontrib><creatorcontrib>Li, Rong-bin</creatorcontrib><creatorcontrib>Li, Hai-yan</creatorcontrib><creatorcontrib>Lin, Lin</creatorcontrib><creatorcontrib>Liu, Chun-xue</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ren, Yi-hong</au><au>Yang, Ting-shu</au><au>Wang, Yu</au><au>Gai, Lu-yue</au><au>Liu, Hong-bin</au><au>Chen, Lian</au><au>Wang, Hong-ye</au><au>Wang, Chun-ya</au><au>Xu, Xiu-li</au><au>Jin, Jing</au><au>Xin, You-hong</au><au>Li, Rong-bin</au><au>Li, Hai-yan</au><au>Lin, Lin</au><au>Liu, Chun-xue</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome</atitle><jtitle>Chinese medical journal</jtitle><addtitle>Chinese Medical Journal</addtitle><date>2008-05-05</date><risdate>2008</risdate><volume>121</volume><issue>9</issue><spage>850</spage><epage>852</epage><pages>850-852</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><abstract>Most cases of acute coronary syndrome (ACS) involve coronary atherosclerosis and plaque rupture, as well as subsequent thrombosis. The initial thrombotic events leading to red thrombus formation are platelet adherence and aggregation. Platelets play a very important role during the establishment and progression of a thrombosis in a coronary artery. Therefore, in recent years guidelines have been developed in an effort to strengthen antiplatelet therapy in ACS, but unfortunately the methods to evaluate platelet activity and the strength of platelet inhibition are lacking.</abstract><cop>China</cop><pub>Department of Cardiology, General Hospital of the Chinese People's Liberation Army, Beijing 100083, China</pub><pmid>18701053</pmid><doi>10.1097/00029330-200805010-00018</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute Coronary Syndrome - drug therapy Angioplasty, Balloon, Coronary Aspirin - administration & dosage Humans Platelet Aggregation Inhibitors - administration & dosage Thrombelastography Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Tyrosine - administration & dosage Tyrosine - analogs & derivatives 急性冠状动脉血栓症 血小板 |
title | Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome |
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