Evaluation of NR2B peptide as subunit vaccines against experimental neuropathic pain

Background NR2B containing N-methyI-D-aspartate （NMDA） receptor plays an important role in the facilitation and maintenance of neuropathic pain. The discrete distribution of NR2B subunit in the central nervous system （CNS） may support reduced side effects of agents that act selectively at this site....

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Veröffentlicht in:	Chinese medical journal 2007-04, Vol.120 (8), p.643-647
Hauptverfasser:	Wang, Gong-Ming, Tian, Yu-Ke, Chen, Jian-Ping, Tian, Xu-Bi, Gao, Feng, Yang, Hui, An, Ke, Ma, Guo-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Animals Blotting, Western Disease Models, Animal Enzyme-Linked Immunosorbent Assay Female Hemocyanins - immunology Immunoglobulin G - immunology Neuralgia - immunology Neuralgia - physiopathology Neuralgia - prevention & control NR2BA肽 Pain Measurement Rats Rats, Sprague-Dawley Receptors, N-Methyl-D-Aspartate - immunology Receptors, N-Methyl-D-Aspartate - metabolism Recombinant Fusion Proteins - administration & dosage Recombinant Fusion Proteins - immunology Spinal Cord - drug effects Spinal Cord - metabolism Spinal Cord - physiopathology Time Factors Vaccines - administration & dosage Vaccines - immunology 实验性神经痛疫苗亚单位神经损伤
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