Propofol evokes endothelium-independent relaxation in rabbit thoracic aorta strips： role of K^＋ channels
Anesthetic induction and maintenance with propofol are associated with the decreased blood pressure that is partly due to their ability to inhibit vascular tone. it was suggested that mechanism of vasodilation induced by propofol may be related to reduction in extracellular Calcium influx and suppre...
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| Veröffentlicht in: | Chinese medical journal 2005-08, Vol.118 (16), p.1388-1391 |
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| creator | Luo, Ai-lin Luo, Tao Liu, Xian-yi |
| description | Anesthetic induction and maintenance with propofol are associated with the decreased blood pressure that is partly due to their ability to inhibit vascular tone. it was suggested that mechanism of vasodilation induced by propofol may be related to reduction in extracellular Calcium influx and suppression of intracellular calcium release. Vascular tone is regulated by several major mechanisms except for calcium channels. One mechanism involves endothelial factors. A second major area of research involves regulation of vascular tone by activity of K^＋ channels. To understand the mechanisms of action of propofol on smooth muscle cells, |
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Vascular tone is regulated by several major mechanisms except for calcium channels. One mechanism involves endothelial factors. A second major area of research involves regulation of vascular tone by activity of K^＋ channels. To understand the mechanisms of action of propofol on smooth muscle cells,</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>PMID: 16157036</identifier><language>eng</language><publisher>China: Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China%Department of Anesthesiology, Remin Hospital, Wuhan University, Wuhan 430074, China</publisher><subject>Anesthetics, Intravenous - pharmacology ; Animals ; Aorta, Thoracic - drug effects ; Aorta, Thoracic - physiology ; Endothelium, Vascular - physiology ; Female ; In Vitro Techniques ; Male ; Norepinephrine - pharmacology ; Potassium Channels - physiology ; Propofol - pharmacology ; Rabbits ; Vasodilation - drug effects ; 内皮功能 ; 动物实验 ; 胸动脉手术 ; 钾离子通道</subject><ispartof>Chinese medical journal, 2005-08, Vol.118 (16), p.1388-1391</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16157036$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Luo, Ai-lin</creatorcontrib><creatorcontrib>Luo, Tao</creatorcontrib><creatorcontrib>Liu, Xian-yi</creatorcontrib><title>Propofol evokes endothelium-independent relaxation in rabbit thoracic aorta strips： role of K^＋ channels</title><title>Chinese medical journal</title><addtitle>Chinese Medical Journal</addtitle><description>Anesthetic induction and maintenance with propofol are associated with the decreased blood pressure that is partly due to their ability to inhibit vascular tone. it was suggested that mechanism of vasodilation induced by propofol may be related to reduction in extracellular Calcium influx and suppression of intracellular calcium release. 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| identifier | ISSN: 0366-6999 |
| ispartof | Chinese medical journal, 2005-08, Vol.118 (16), p.1388-1391 |
| issn | 0366-6999 2542-5641 |
| language | eng |
| recordid | cdi_wanfang_journals_zhcmj200516012 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Anesthetics, Intravenous - pharmacology Animals Aorta, Thoracic - drug effects Aorta, Thoracic - physiology Endothelium, Vascular - physiology Female In Vitro Techniques Male Norepinephrine - pharmacology Potassium Channels - physiology Propofol - pharmacology Rabbits Vasodilation - drug effects 内皮功能 动物实验 胸动脉手术 钾离子通道 |
| title | Propofol evokes endothelium-independent relaxation in rabbit thoracic aorta strips： role of K^＋ channels |
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