Misoprostol in labour induction of term pregnancy： a meta-analysis
Objective To evaluate the efficacy and safety of misoprostol in term labour induction. Data sources Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour...
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| Veröffentlicht in: | Chinese medical journal 2004-03, Vol.117 (3), p.449-452 |
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| creator | 李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯 |
| description | Objective To evaluate the efficacy and safety of misoprostol in term labour induction. Data sources Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand searches of reference lists of original studies and reviews (including meta-analyses) and contact with investigators in this field before 2001. Study selection Studies were included if they had data on misoprostol and labour induction Altogether 623 articles were found and 124 were admitted, including 19 287 cases. Data extraction Data were collected on efficacy and incidence of side-effects of misoprostol and oxytocin. Data were checked for consistency within the published articles and converted into a standard format for incorporation into a central database. Data synthesis The average successful induction rate, rates of caesarean section; incidence of tachysystole, hypertonus of uterus and precipitous labour, and rates of meconium stained amniotic fluid between the misoprostol and oxytocin groups were significantly different (P |
| format | Article |
| fullrecord | <record><control><sourceid>wanfang_jour_pubme</sourceid><recordid>TN_cdi_wanfang_journals_zhcmj200403025</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>9534969</cqvip_id><wanfj_id>zhcmj200403025</wanfj_id><sourcerecordid>zhcmj200403025</sourcerecordid><originalsourceid>FETCH-LOGICAL-c264t-92098312e7a0ee158e57986a8ae16454a094d0cb4880524b7ddfaab0839b253d3</originalsourceid><addsrcrecordid>eNo1j0tOwzAYhC0EoqVwBWQ27CI5fsVeIt5SERtYR78dp3VJ7BCnQuUonIU7cQUsFVYzi0-fZg7QnApOCyF5eYjmhElZSK31DJ2ktCGEClHJYzQrBeGs0mSObp58isMY0xQ77APuwMTtmFuztZOPAccWT27s8TC6VYBgdz_fXxhw7yYoIEC3Sz6doqMWuuTO_nKBXu9uX64fiuXz_eP11bKwVPKp0JRoxUrqKiDOlUI5UWklQYErJRcciOYNsYYrRQTlpmqaFsAQxbShgjVsgS733g8ILYRVvclb84ZUf65tv6GEcMLyyQye78Fha3rX1MPoexh39f_vDFzsAbuOYfXus8uAfWt952otGNdSs1_Y3mCA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Misoprostol in labour induction of term pregnancy： a meta-analysis</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</creator><creatorcontrib>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</creatorcontrib><description>Objective To evaluate the efficacy and safety of misoprostol in term labour induction. Data sources Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand searches of reference lists of original studies and reviews (including meta-analyses) and contact with investigators in this field before 2001. Study selection Studies were included if they had data on misoprostol and labour induction Altogether 623 articles were found and 124 were admitted, including 19 287 cases. Data extraction Data were collected on efficacy and incidence of side-effects of misoprostol and oxytocin. Data were checked for consistency within the published articles and converted into a standard format for incorporation into a central database. Data synthesis The average successful induction rate, rates of caesarean section; incidence of tachysystole, hypertonus of uterus and precipitous labour, and rates of meconium stained amniotic fluid between the misoprostol and oxytocin groups were significantly different (P<0.05). There were no significant differences between the two groups concerning the average interval from the administration of misoprostol and oxytocin to the onset of labour, duration of the total stage of labour, incidence rate of foetal distress, neonatal asphyxia ( 1-minute Apgar score ≤7 ), postpartum haemorrhage or amount of blood loss in postpartum. Conclusions Misoprostol is a superior agent over oxytocin on the induction of term labour, but its application might increase the risk of precipitatous labour, abnormal uterine contractions or meconium stained amniotic fluid. Therefore, the doasges and regimens of the agent need further investigation.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>PMID: 15043790</identifier><language>eng</language><publisher>China: Department of Obstetrics and Gynaecology,Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China</publisher><subject>Female ; Humans ; Labor, Induced - methods ; meta-分析 ; Misoprostol - adverse effects ; Oxytocics - adverse effects ; Oxytocin ; Pregnancy ; Safety ; 人工流产 ; 安全性 ; 用药途径 ; 米索前列醇</subject><ispartof>Chinese medical journal, 2004-03, Vol.117 (3), p.449-452</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15043790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</creatorcontrib><title>Misoprostol in labour induction of term pregnancy： a meta-analysis</title><title>Chinese medical journal</title><addtitle>Chinese Medical Journal</addtitle><description>Objective To evaluate the efficacy and safety of misoprostol in term labour induction. Data sources Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand searches of reference lists of original studies and reviews (including meta-analyses) and contact with investigators in this field before 2001. Study selection Studies were included if they had data on misoprostol and labour induction Altogether 623 articles were found and 124 were admitted, including 19 287 cases. Data extraction Data were collected on efficacy and incidence of side-effects of misoprostol and oxytocin. Data were checked for consistency within the published articles and converted into a standard format for incorporation into a central database. Data synthesis The average successful induction rate, rates of caesarean section; incidence of tachysystole, hypertonus of uterus and precipitous labour, and rates of meconium stained amniotic fluid between the misoprostol and oxytocin groups were significantly different (P<0.05). There were no significant differences between the two groups concerning the average interval from the administration of misoprostol and oxytocin to the onset of labour, duration of the total stage of labour, incidence rate of foetal distress, neonatal asphyxia ( 1-minute Apgar score ≤7 ), postpartum haemorrhage or amount of blood loss in postpartum. Conclusions Misoprostol is a superior agent over oxytocin on the induction of term labour, but its application might increase the risk of precipitatous labour, abnormal uterine contractions or meconium stained amniotic fluid. Therefore, the doasges and regimens of the agent need further investigation.</description><subject>Female</subject><subject>Humans</subject><subject>Labor, Induced - methods</subject><subject>meta-分析</subject><subject>Misoprostol - adverse effects</subject><subject>Oxytocics - adverse effects</subject><subject>Oxytocin</subject><subject>Pregnancy</subject><subject>Safety</subject><subject>人工流产</subject><subject>安全性</subject><subject>用药途径</subject><subject>米索前列醇</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0tOwzAYhC0EoqVwBWQ27CI5fsVeIt5SERtYR78dp3VJ7BCnQuUonIU7cQUsFVYzi0-fZg7QnApOCyF5eYjmhElZSK31DJ2ktCGEClHJYzQrBeGs0mSObp58isMY0xQ77APuwMTtmFuztZOPAccWT27s8TC6VYBgdz_fXxhw7yYoIEC3Sz6doqMWuuTO_nKBXu9uX64fiuXz_eP11bKwVPKp0JRoxUrqKiDOlUI5UWklQYErJRcciOYNsYYrRQTlpmqaFsAQxbShgjVsgS733g8ILYRVvclb84ZUf65tv6GEcMLyyQye78Fha3rX1MPoexh39f_vDFzsAbuOYfXus8uAfWt952otGNdSs1_Y3mCA</recordid><startdate>20040301</startdate><enddate>20040301</enddate><creator>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</creator><general>Department of Obstetrics and Gynaecology,Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20040301</creationdate><title>Misoprostol in labour induction of term pregnancy： a meta-analysis</title><author>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c264t-92098312e7a0ee158e57986a8ae16454a094d0cb4880524b7ddfaab0839b253d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Female</topic><topic>Humans</topic><topic>Labor, Induced - methods</topic><topic>meta-分析</topic><topic>Misoprostol - adverse effects</topic><topic>Oxytocics - adverse effects</topic><topic>Oxytocin</topic><topic>Pregnancy</topic><topic>Safety</topic><topic>人工流产</topic><topic>安全性</topic><topic>用药途径</topic><topic>米索前列醇</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>李小毛 万璟 许成芳 张宇 方莉 史众杰 李凯</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Misoprostol in labour induction of term pregnancy： a meta-analysis</atitle><jtitle>Chinese medical journal</jtitle><addtitle>Chinese Medical Journal</addtitle><date>2004-03-01</date><risdate>2004</risdate><volume>117</volume><issue>3</issue><spage>449</spage><epage>452</epage><pages>449-452</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><abstract>Objective To evaluate the efficacy and safety of misoprostol in term labour induction. Data sources Data from published English and Chinese literatures about misoprostol in term labour induction were identified from Medline and CBMdisk (using the search terms "misoprostol" and "labour induction") before 2001; hand searches of reference lists of original studies and reviews (including meta-analyses) and contact with investigators in this field before 2001. Study selection Studies were included if they had data on misoprostol and labour induction Altogether 623 articles were found and 124 were admitted, including 19 287 cases. Data extraction Data were collected on efficacy and incidence of side-effects of misoprostol and oxytocin. Data were checked for consistency within the published articles and converted into a standard format for incorporation into a central database. Data synthesis The average successful induction rate, rates of caesarean section; incidence of tachysystole, hypertonus of uterus and precipitous labour, and rates of meconium stained amniotic fluid between the misoprostol and oxytocin groups were significantly different (P<0.05). There were no significant differences between the two groups concerning the average interval from the administration of misoprostol and oxytocin to the onset of labour, duration of the total stage of labour, incidence rate of foetal distress, neonatal asphyxia ( 1-minute Apgar score ≤7 ), postpartum haemorrhage or amount of blood loss in postpartum. Conclusions Misoprostol is a superior agent over oxytocin on the induction of term labour, but its application might increase the risk of precipitatous labour, abnormal uterine contractions or meconium stained amniotic fluid. Therefore, the doasges and regimens of the agent need further investigation.</abstract><cop>China</cop><pub>Department of Obstetrics and Gynaecology,Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China</pub><pmid>15043790</pmid><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0366-6999 |
| ispartof | Chinese medical journal, 2004-03, Vol.117 (3), p.449-452 |
| issn | 0366-6999 2542-5641 |
| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Female Humans Labor, Induced - methods meta-分析 Misoprostol - adverse effects Oxytocics - adverse effects Oxytocin Pregnancy Safety 人工流产 安全性 用药途径 米索前列醇 |
| title | Misoprostol in labour induction of term pregnancy： a meta-analysis |
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