Detection of hepatitis B virus polymerase variations resistant to lamivudine therapy

To investigate variations in hepatitis B virus (HBV) polymerase gene in chronic HBV infected patients resistant to lamivudine therapy. Specimens were obtained from nine patients with chronic HBV infection, who were resistant to lamivudine therapy. Partial segments of the HBV DNA polymerase gene were...

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Veröffentlicht in:	Chinese medical journal 2000-05, Vol.113 (5), p.455-457
Hauptverfasser:	Zhang, X, Han, Y, Lu, Z, Zhang, D, Cai, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Drug Resistance, Microbial Gene Products, pol - genetics Hepatitis B virus - genetics Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - genetics Humans Lamivudine - pharmacology Lamivudine - therapeutic use Polymerase Chain Reaction
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