Opening blood-brain-barrier by intracarotid infusion of papaverine in treatment of malignant cerebral glioma

To find an effective method for the treatment of malignant cerebral glioma by opening the blood-brain-barrier (BBB). The concentration of methotrexate (MTX) in tumor was measured in 18 patients with cerebral glioma, and 155 patients with malignant glioma were treated by intracarotid infusion of papa...

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Veröffentlicht in:	Chinese medical journal 1998-08, Vol.111 (8), p.751-753
Hauptverfasser:	Xue, H, Wang, H, Kong, L, Zhou, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antimetabolites, Antineoplastic - administration & dosage Blood-Brain Barrier - drug effects Brain Neoplasms - drug therapy Carotid Artery, Internal Child Female Glioblastoma - drug therapy Glioma - drug therapy Humans Infusions, Intra-Arterial Male Methotrexate - administration & dosage Middle Aged Papaverine - administration & dosage Vasodilator Agents - administration & dosage
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