The Anatomic Pathology Evaluation of Liver with Diethylinitrosamine Treated via Intraperitoneal Injection Singly and Peros for 90 Days Carcinogenicity Study in F344 Rats

Objective:To establish the integrity experiment method of short( medium)- term carcinogenicity test pursuant to GLP, make into relative SOP and improve the safeguard in the center. Methods:Diethylinitrosamine(DEN) is known as carcinogenic agent, whose target organ is liver. Using the two-stage carci...

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Veröffentlicht in:Chinese journal of biomedical engineering 2008, Vol.17 (2), p.54-60
1. Verfasser: LI Shan-shan ZHANG Lin LI Bao-wen LANG Shu-hui YANG Yan-wei ZHANG Di ZHANG Yang NARAMA Isao KAWAYI Zeshow KANEKO Toyozo XING Rui-chang WANG Xiu-wen LI Bo
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Sprache:eng
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