Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study
In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 y...
Gespeichert in:
| Veröffentlicht in: | Neural regeneration research 2012-04, Vol.7 (11), p.862-866 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 866 |
|---|---|
| container_issue | 11 |
| container_start_page | 862 |
| container_title | Neural regeneration research |
| container_volume | 7 |
| creator | Wang, Naizhi Guo, Yingying Yang, Lili Fu, Wenyi Xu, Yanbing Hou, Linxin Zhao, Shuai Zhang, Ning |
| description | In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment （mean 16 months）. The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8% （7/80）, which was significantly higher than the conventional treatment group （2.6%; 4/156）. The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41 （95% confidence interval： 1.03 11.31）. Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy. Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy. |
| doi_str_mv | 10.3969/j.issn.1673-5374.2012.11.011 |
| format | Article |
| fullrecord | <record><control><sourceid>wanfang_jour_proqu</sourceid><recordid>TN_cdi_wanfang_journals_zgsjzsyj_e201211011</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>41822687</cqvip_id><wanfj_id>zgsjzsyj_e201211011</wanfj_id><sourcerecordid>zgsjzsyj_e201211011</sourcerecordid><originalsourceid>FETCH-LOGICAL-c301t-9160a1168e9d69a2779b0c196dff3b438e07cc7a5db9bf7521579593d0d991f03</originalsourceid><addsrcrecordid>eNpd0Mtq3DAUBmBTWpo07SsUlXZRKHZ1pJFkLUNILxDopl0bWZexzFhyJJkwefoqTKaLrnQEH790_qb5BLijksuvc-dzDh1wQVtGxa4jGEgH0GGAF80l9IK3QrL-ZZ3P5qJ5k_OMMesloa-bC8IEFQLYZRNvnbO6oOhQ2ZaYULA6xewzckqXevdh8qOvU0YxoDTZbVEleoNUKlPyxefWB7Npa9Bqk18nm9ShpmwprqpMR3SNdJxiKiiXzRzfNq-cOmT77vm8av58u_1986O9-_X95831XasphtJK4FgB8N5Kw6UiQsgRa5DcOEfHHe0tFloLxcwoRycYAVZ3ltRgIyU4TK-aL6fcBxWcCvthjlsK9cXhcZ_nx3ycB_tUHECtrerPJ72meL_ZXIbFZ20PBxVs3PIAnGNJGBOi0o__0X_JhPakf4qjVb1_Vtu4WDOsyS8qHYdz8RV8OAE9xbC_9_WHZ7ODnhDeC_oXGX-UTg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2382801133</pqid></control><display><type>article</type><title>Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study</title><source>Medknow Open Access Medical Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Journals@Ovid Complete</source><source>PubMed Central Open Access</source><creator>Wang, Naizhi ; Guo, Yingying ; Yang, Lili ; Fu, Wenyi ; Xu, Yanbing ; Hou, Linxin ; Zhao, Shuai ; Zhang, Ning</creator><creatorcontrib>Wang, Naizhi ; Guo, Yingying ; Yang, Lili ; Fu, Wenyi ; Xu, Yanbing ; Hou, Linxin ; Zhao, Shuai ; Zhang, Ning</creatorcontrib><description>In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment （mean 16 months）. The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8% （7/80）, which was significantly higher than the conventional treatment group （2.6%; 4/156）. The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41 （95% confidence interval： 1.03 11.31）. Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy. Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy.</description><identifier>ISSN: 1673-5374</identifier><identifier>EISSN: 1876-7958</identifier><identifier>DOI: 10.3969/j.issn.1673-5374.2012.11.011</identifier><identifier>PMID: 25737715</identifier><language>eng</language><publisher>India: Medknow Publications & Media Pvt. Ltd</publisher><subject>Biopsy ; Cohort analysis ; Guillain-Barre syndrome ; Immunology ; Infections ; Monoclonal antibodies ; Necrosis ; Nervous system ; Neurological disorders ; Patients ; Peripheral neuropathy ; Rheumatoid arthritis ; Rheumatology ; Studies ; TNF inhibitors ; Tumor necrosis factor-TNF ; 周围神经 ; 抑制剂 ; 治疗 ; 病变 ; 类风湿关节炎 ; 置信区间 ; 肿瘤坏死因子 ; 队列研究</subject><ispartof>Neural regeneration research, 2012-04, Vol.7 (11), p.862-866</ispartof><rights>2012. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/88507X/88507X.jpg</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25737715$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Naizhi</creatorcontrib><creatorcontrib>Guo, Yingying</creatorcontrib><creatorcontrib>Yang, Lili</creatorcontrib><creatorcontrib>Fu, Wenyi</creatorcontrib><creatorcontrib>Xu, Yanbing</creatorcontrib><creatorcontrib>Hou, Linxin</creatorcontrib><creatorcontrib>Zhao, Shuai</creatorcontrib><creatorcontrib>Zhang, Ning</creatorcontrib><title>Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study</title><title>Neural regeneration research</title><addtitle>Neural Regeneration Research</addtitle><description>In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment （mean 16 months）. The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8% （7/80）, which was significantly higher than the conventional treatment group （2.6%; 4/156）. The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41 （95% confidence interval： 1.03 11.31）. Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy. Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy.</description><subject>Biopsy</subject><subject>Cohort analysis</subject><subject>Guillain-Barre syndrome</subject><subject>Immunology</subject><subject>Infections</subject><subject>Monoclonal antibodies</subject><subject>Necrosis</subject><subject>Nervous system</subject><subject>Neurological disorders</subject><subject>Patients</subject><subject>Peripheral neuropathy</subject><subject>Rheumatoid arthritis</subject><subject>Rheumatology</subject><subject>Studies</subject><subject>TNF inhibitors</subject><subject>Tumor necrosis factor-TNF</subject><subject>周围神经</subject><subject>抑制剂</subject><subject>治疗</subject><subject>病变</subject><subject>类风湿关节炎</subject><subject>置信区间</subject><subject>肿瘤坏死因子</subject><subject>队列研究</subject><issn>1673-5374</issn><issn>1876-7958</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpd0Mtq3DAUBmBTWpo07SsUlXZRKHZ1pJFkLUNILxDopl0bWZexzFhyJJkwefoqTKaLrnQEH790_qb5BLijksuvc-dzDh1wQVtGxa4jGEgH0GGAF80l9IK3QrL-ZZ3P5qJ5k_OMMesloa-bC8IEFQLYZRNvnbO6oOhQ2ZaYULA6xewzckqXevdh8qOvU0YxoDTZbVEleoNUKlPyxefWB7Npa9Bqk18nm9ShpmwprqpMR3SNdJxiKiiXzRzfNq-cOmT77vm8av58u_1986O9-_X95831XasphtJK4FgB8N5Kw6UiQsgRa5DcOEfHHe0tFloLxcwoRycYAVZ3ltRgIyU4TK-aL6fcBxWcCvthjlsK9cXhcZ_nx3ycB_tUHECtrerPJ72meL_ZXIbFZ20PBxVs3PIAnGNJGBOi0o__0X_JhPakf4qjVb1_Vtu4WDOsyS8qHYdz8RV8OAE9xbC_9_WHZ7ODnhDeC_oXGX-UTg</recordid><startdate>20120415</startdate><enddate>20120415</enddate><creator>Wang, Naizhi</creator><creator>Guo, Yingying</creator><creator>Yang, Lili</creator><creator>Fu, Wenyi</creator><creator>Xu, Yanbing</creator><creator>Hou, Linxin</creator><creator>Zhao, Shuai</creator><creator>Zhang, Ning</creator><general>Medknow Publications & Media Pvt. Ltd</general><general>Department of Rheumatism, Shengjing Hospital, China Medical University, Shenyang 110004, Liaoning Province, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M2M</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20120415</creationdate><title>Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study</title><author>Wang, Naizhi ; Guo, Yingying ; Yang, Lili ; Fu, Wenyi ; Xu, Yanbing ; Hou, Linxin ; Zhao, Shuai ; Zhang, Ning</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c301t-9160a1168e9d69a2779b0c196dff3b438e07cc7a5db9bf7521579593d0d991f03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Biopsy</topic><topic>Cohort analysis</topic><topic>Guillain-Barre syndrome</topic><topic>Immunology</topic><topic>Infections</topic><topic>Monoclonal antibodies</topic><topic>Necrosis</topic><topic>Nervous system</topic><topic>Neurological disorders</topic><topic>Patients</topic><topic>Peripheral neuropathy</topic><topic>Rheumatoid arthritis</topic><topic>Rheumatology</topic><topic>Studies</topic><topic>TNF inhibitors</topic><topic>Tumor necrosis factor-TNF</topic><topic>周围神经</topic><topic>抑制剂</topic><topic>治疗</topic><topic>病变</topic><topic>类风湿关节炎</topic><topic>置信区间</topic><topic>肿瘤坏死因子</topic><topic>队列研究</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Naizhi</creatorcontrib><creatorcontrib>Guo, Yingying</creatorcontrib><creatorcontrib>Yang, Lili</creatorcontrib><creatorcontrib>Fu, Wenyi</creatorcontrib><creatorcontrib>Xu, Yanbing</creatorcontrib><creatorcontrib>Hou, Linxin</creatorcontrib><creatorcontrib>Zhao, Shuai</creatorcontrib><creatorcontrib>Zhang, Ning</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest Psychology</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Neural regeneration research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Naizhi</au><au>Guo, Yingying</au><au>Yang, Lili</au><au>Fu, Wenyi</au><au>Xu, Yanbing</au><au>Hou, Linxin</au><au>Zhao, Shuai</au><au>Zhang, Ning</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study</atitle><jtitle>Neural regeneration research</jtitle><addtitle>Neural Regeneration Research</addtitle><date>2012-04-15</date><risdate>2012</risdate><volume>7</volume><issue>11</issue><spage>862</spage><epage>866</epage><pages>862-866</pages><issn>1673-5374</issn><eissn>1876-7958</eissn><abstract>In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment （mean 16 months）. The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8% （7/80）, which was significantly higher than the conventional treatment group （2.6%; 4/156）. The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41 （95% confidence interval： 1.03 11.31）. Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy. Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy.</abstract><cop>India</cop><pub>Medknow Publications & Media Pvt. Ltd</pub><pmid>25737715</pmid><doi>10.3969/j.issn.1673-5374.2012.11.011</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1673-5374 |
| ispartof | Neural regeneration research, 2012-04, Vol.7 (11), p.862-866 |
| issn | 1673-5374 1876-7958 |
| language | eng |
| recordid | cdi_wanfang_journals_zgsjzsyj_e201211011 |
| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; Journals@Ovid Complete; PubMed Central Open Access |
| subjects | Biopsy Cohort analysis Guillain-Barre syndrome Immunology Infections Monoclonal antibodies Necrosis Nervous system Neurological disorders Patients Peripheral neuropathy Rheumatoid arthritis Rheumatology Studies TNF inhibitors Tumor necrosis factor-TNF 周围神经 抑制剂 治疗 病变 类风湿关节炎 置信区间 肿瘤坏死因子 队列研究 |
| title | Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T05%3A09%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wanfang_jour_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20tumor%20necrosis%20factor%20inhibitors%20on%20rheumatoid%20arthritis-induced%20peripheral%20neuropathy%20A%20cohort%20study&rft.jtitle=Neural%20regeneration%20research&rft.au=Wang,%20Naizhi&rft.date=2012-04-15&rft.volume=7&rft.issue=11&rft.spage=862&rft.epage=866&rft.pages=862-866&rft.issn=1673-5374&rft.eissn=1876-7958&rft_id=info:doi/10.3969/j.issn.1673-5374.2012.11.011&rft_dat=%3Cwanfang_jour_proqu%3Ezgsjzsyj_e201211011%3C/wanfang_jour_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2382801133&rft_id=info:pmid/25737715&rft_cqvip_id=41822687&rft_wanfj_id=zgsjzsyj_e201211011&rfr_iscdi=true |