Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province
Currently it is not well known whether apolipoprotein E （ApoE） is a genetic susceptibility factor for cerebrovascular diseases in the Chinese Naxi population. The present study detected and sequenced ApoE polymorphisms of 90 patients with cerebrovascular diseases （58 cases of cerebral infarction and...
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| Veröffentlicht in: | 中国神经再生研究（英文版） 2011-03, Vol.6 (9), p.712-716 |
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| creator | Hong Xu Qihong Yuan Xijun Fan Guoqiang He |
| description | Currently it is not well known whether apolipoprotein E （ApoE） is a genetic susceptibility factor for cerebrovascular diseases in the Chinese Naxi population. The present study detected and sequenced ApoE polymorphisms of 90 patients with cerebrovascular diseases （58 cases of cerebral infarction and 32 cases of intracerebral hemorrhage）, and 50 normal people of Naxi nationality from Yunnan province, China. The populations were used to analyze the relationship of ApoE polymorphisms with cerebral infarction and intracerebral hemorrhage. Results showed an association between ApoE gene polymorphism and the onset of cerebral infarction, and a possibility that the ε4 allele is a susceptibility locus for the risk of cerebral infarction. However, there was no evidence of a relationship between the ApoE gene polymorphism and cerebral hemorrhage. |
| doi_str_mv | 10.3969/j.issn.1673-5374.2011.09.013 |
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However, there was no evidence of a relationship between the ApoE gene polymorphism and cerebral hemorrhage.</description><identifier>ISSN: 1673-5374</identifier><identifier>DOI: 10.3969/j.issn.1673-5374.2011.09.013</identifier><language>eng</language><publisher>Department of Neurology, First Affifiated Hospital of Kunming Medical College, Kunming 650032, Yunnan Province, China%Department of Neurology, First People's Hospital of Lijiang, Lijiang 671000, Yunnan Province, China</publisher><subject>ApoE基因 ; 中国 ; 云南省 ; 人口 ; 基因多态性 ; 纳西族 ; 脑血管疾病 ; 载脂蛋白E</subject><ispartof>中国神经再生研究（英文版）, 2011-03, Vol.6 (9), p.712-716</ispartof><rights>Copyright © Wanfang Data Co. Ltd. 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The present study detected and sequenced ApoE polymorphisms of 90 patients with cerebrovascular diseases （58 cases of cerebral infarction and 32 cases of intracerebral hemorrhage）, and 50 normal people of Naxi nationality from Yunnan province, China. The populations were used to analyze the relationship of ApoE polymorphisms with cerebral infarction and intracerebral hemorrhage. Results showed an association between ApoE gene polymorphism and the onset of cerebral infarction, and a possibility that the ε4 allele is a susceptibility locus for the risk of cerebral infarction. However, there was no evidence of a relationship between the ApoE gene polymorphism and cerebral hemorrhage.</description><subject>ApoE基因</subject><subject>中国</subject><subject>云南省</subject><subject>人口</subject><subject>基因多态性</subject><subject>纳西族</subject><subject>脑血管疾病</subject><subject>载脂蛋白E</subject><issn>1673-5374</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNo9kMtOwzAQRb0AiVL4ByOxQwl2HMfxsqrKQ6pgAwtWkeNMEkeNHey20H49rkCsZnR0Zq50EbqlJGWykPdDakKwKS0ESzgTeZoRSlMiU0LZGZr98wt0GcJACC9lxmYoLCa3MZObvNuCsXiFO7CAIzyMzk-9CSOOWIOH2ru9Cnq3UR43JoAKELBr8bYHvOyNhQD4RX2beDxFaWucDbj1bsQfO2uVxTFjb6yGK3Teqk2A6785R-8Pq7flU7J-fXxeLtaJzqjYJlBLXudKlyA0pbyooSll3lJdC8g5FTIrRZNldSsE5wK4aGRd6KzJm7gTqdgc3f3-_VK2VbarBrfzNiZWxy4Mx3AYKji1RGTsKNo3v7bune0-TfQnb0blDxUTZXFKZD9rem-R</recordid><startdate>20110325</startdate><enddate>20110325</enddate><creator>Hong Xu Qihong Yuan Xijun Fan Guoqiang He</creator><general>Department of Neurology, First Affifiated Hospital of Kunming Medical College, Kunming 650032, Yunnan Province, China%Department of Neurology, First People's Hospital of Lijiang, Lijiang 671000, Yunnan Province, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20110325</creationdate><title>Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province</title><author>Hong Xu Qihong Yuan Xijun Fan Guoqiang He</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c217t-eb95b4ac8e7c1156bed894f1cb7e45179287d22bf77557e57d9b6c2d4de5709a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>ApoE基因</topic><topic>中国</topic><topic>云南省</topic><topic>人口</topic><topic>基因多态性</topic><topic>纳西族</topic><topic>脑血管疾病</topic><topic>载脂蛋白E</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hong Xu Qihong Yuan Xijun Fan Guoqiang He</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>中国神经再生研究（英文版）</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hong Xu Qihong Yuan Xijun Fan Guoqiang He</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province</atitle><jtitle>中国神经再生研究（英文版）</jtitle><addtitle>Neural Regeneration Research</addtitle><date>2011-03-25</date><risdate>2011</risdate><volume>6</volume><issue>9</issue><spage>712</spage><epage>716</epage><pages>712-716</pages><issn>1673-5374</issn><abstract>Currently it is not well known whether apolipoprotein E （ApoE） is a genetic susceptibility factor for cerebrovascular diseases in the Chinese Naxi population. 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| identifier | ISSN: 1673-5374 |
| ispartof | 中国神经再生研究（英文版）, 2011-03, Vol.6 (9), p.712-716 |
| issn | 1673-5374 |
| language | eng |
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| source | Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | ApoE基因 中国 云南省 人口 基因多态性 纳西族 脑血管疾病 载脂蛋白E |
| title | Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province |
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