甲状旁腺激素1型受体在肾脏疾病中的研究进展
R692.9%R392.11; 甲状旁腺激素1型受体(PTH1R)是G蛋白偶联受体家族成员之一,在体内广泛表达,参与体内胚胎发育、钙磷稳态、机体代谢、肿瘤发生等多种过程.PTH1R在肾脏中高度表达,PTH1R的活化可涉及多种复杂机制,参与肾脏疾病的发生、发展,与多种肾脏疾病如糖尿病肾病、肾小球肾炎、急性肾损伤、慢性肾脏病等关系密切.本文就PTH1R功能及其在肾脏疾病中发挥的作用和机制进行综述,深入探讨PTH1R与肾脏疾病的关系和相关机制,以期为肾脏疾病的诊断和治疗提供新思路....
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| Veröffentlicht in: | 中国全科医学 2023-04, Vol.26 (11), p.1398-1403 |
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| container_title | 中国全科医学 |
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| creator | 鄢鹏 宋健玲 房向东 |
| description | R692.9%R392.11; 甲状旁腺激素1型受体(PTH1R)是G蛋白偶联受体家族成员之一,在体内广泛表达,参与体内胚胎发育、钙磷稳态、机体代谢、肿瘤发生等多种过程.PTH1R在肾脏中高度表达,PTH1R的活化可涉及多种复杂机制,参与肾脏疾病的发生、发展,与多种肾脏疾病如糖尿病肾病、肾小球肾炎、急性肾损伤、慢性肾脏病等关系密切.本文就PTH1R功能及其在肾脏疾病中发挥的作用和机制进行综述,深入探讨PTH1R与肾脏疾病的关系和相关机制,以期为肾脏疾病的诊断和治疗提供新思路. |
| doi_str_mv | 10.12114/j.issn.1007-9572.2022.0523 |
| format | Article |
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| language | chi |
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| source | DOAJ Directory of Open Access Journals |
| title | 甲状旁腺激素1型受体在肾脏疾病中的研究进展 |
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