DC-SIGN and Immunoregulation
Dendritic cells （DCs） are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-typ...
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| Veröffentlicht in: | Cellular & molecular immunology 2006-08, Vol.3 (4), p.279-283 |
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| creator | Zhou, Tong Chen, Yongxi Hao, Li Zhang, Yanyun |
| description | Dendritic cells （DCs） are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. These studies on DC-SIGN involved in primary and secondary immune response and relevant mechanism will certainly provide us with a new method in treating and preventing certain diseases. |
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These studies on DC-SIGN involved in primary and secondary immune response and relevant mechanism will certainly provide us with a new method in treating and preventing certain diseases.</description><identifier>ISSN: 1672-7681</identifier><identifier>EISSN: 2042-0226</identifier><identifier>PMID: 16978536</identifier><language>eng</language><publisher>China: Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai 200025, China%Shanghai Institute of Immunology and Institute of Health Sciences,Shanghai Institute of Biological Sciences, Shanghai Jiao Tong University,Shanghai 200025, China</publisher><subject>Cell Adhesion Molecules - chemistry ; Cell Adhesion Molecules - physiology ; Dendritic Cells - immunology ; Humans ; Immunity ; Lectins, C-Type - chemistry ; Lectins, C-Type - physiology ; Receptors, Cell Surface - chemistry ; Receptors, Cell Surface - physiology ; Receptors, Pattern Recognition - immunology ; Tumor Escape - immunology ; 免疫控制 ; 免疫调节 ; 图形识别 ; 生物学</subject><ispartof>Cellular & molecular immunology, 2006-08, Vol.3 (4), p.279-283</ispartof><rights>Copyright © Wanfang Data Co. 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It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. These studies on DC-SIGN involved in primary and secondary immune response and relevant mechanism will certainly provide us with a new method in treating and preventing certain diseases.</description><subject>Cell Adhesion Molecules - chemistry</subject><subject>Cell Adhesion Molecules - physiology</subject><subject>Dendritic Cells - immunology</subject><subject>Humans</subject><subject>Immunity</subject><subject>Lectins, C-Type - chemistry</subject><subject>Lectins, C-Type - physiology</subject><subject>Receptors, Cell Surface - chemistry</subject><subject>Receptors, Cell Surface - physiology</subject><subject>Receptors, Pattern Recognition - immunology</subject><subject>Tumor Escape - immunology</subject><subject>免疫控制</subject><subject>免疫调节</subject><subject>图形识别</subject><subject>生物学</subject><issn>1672-7681</issn><issn>2042-0226</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z81Kw0AUBeBBFFurbyBSXLgQAnd-MjNZStUaKLpQ18NkchNTk0mbNGj79A6kri5cPs7hnJApA8EiYEyekimVikVKajohF32_Boi1UOKcTKhMlI65nJLrx0X0ni5f59bn87RpBt92WA613VWtvyRnha17vDreGfl8fvpYvESrt2W6eFhFjim6i3LQmhfAhcg4Jg4lcOlEIhxzsc5dlkGucsoKjpBowa0SFARC-BTOWYt8Ru7H3B_rC-tLs26HzodGcyib_e_hYJABSBBhQcB3I9507XbAfmeaqndY19ZjO_RGah0nkrEAb45wyBrMzaarGtvtzf_4AG5H4L5aX26rUJxZ911UNRrGEqpjofgf5GRfpg</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Zhou, Tong</creator><creator>Chen, Yongxi</creator><creator>Hao, Li</creator><creator>Zhang, Yanyun</creator><general>Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai 200025, China%Shanghai Institute of Immunology and Institute of Health Sciences,Shanghai Institute of Biological Sciences, Shanghai Jiao Tong University,Shanghai 200025, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20060801</creationdate><title>DC-SIGN and Immunoregulation</title><author>Zhou, Tong ; Chen, Yongxi ; Hao, Li ; Zhang, Yanyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c271t-d0883f0344b3e9ce6036c494c2c58dcbb0d7d12f3e09843a74104e012ffccaae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Cell Adhesion Molecules - chemistry</topic><topic>Cell Adhesion Molecules - physiology</topic><topic>Dendritic Cells - immunology</topic><topic>Humans</topic><topic>Immunity</topic><topic>Lectins, C-Type - chemistry</topic><topic>Lectins, C-Type - physiology</topic><topic>Receptors, Cell Surface - chemistry</topic><topic>Receptors, Cell Surface - physiology</topic><topic>Receptors, Pattern Recognition - immunology</topic><topic>Tumor Escape - immunology</topic><topic>免疫控制</topic><topic>免疫调节</topic><topic>图形识别</topic><topic>生物学</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhou, Tong</creatorcontrib><creatorcontrib>Chen, Yongxi</creatorcontrib><creatorcontrib>Hao, Li</creatorcontrib><creatorcontrib>Zhang, Yanyun</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Cellular & molecular immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhou, Tong</au><au>Chen, Yongxi</au><au>Hao, Li</au><au>Zhang, Yanyun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DC-SIGN and Immunoregulation</atitle><jtitle>Cellular & molecular immunology</jtitle><addtitle>Cellular ＆ Molecular Immunology</addtitle><date>2006-08-01</date><risdate>2006</risdate><volume>3</volume><issue>4</issue><spage>279</spage><epage>283</epage><pages>279-283</pages><issn>1672-7681</issn><eissn>2042-0226</eissn><abstract>Dendritic cells （DCs） are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. 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| ispartof | Cellular & molecular immunology, 2006-08, Vol.3 (4), p.279-283 |
| issn | 1672-7681 2042-0226 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - physiology Dendritic Cells - immunology Humans Immunity Lectins, C-Type - chemistry Lectins, C-Type - physiology Receptors, Cell Surface - chemistry Receptors, Cell Surface - physiology Receptors, Pattern Recognition - immunology Tumor Escape - immunology 免疫控制 免疫调节 图形识别 生物学 |
| title | DC-SIGN and Immunoregulation |
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