CuBr-promoted domino Biginelli reaction for the diastereoselective synthesis of bridged polyheterocycles: Mechanism studies and in vitro anti-tumor activities

The low-cost CuBr-promoted domino Biginelli reaction among readily available ketones, salicylaldehyde derivatives and 3-amino-1,2,4-triazole was studied under solvothermal conditions, giving the novel bridged polyheterocycles bearing two or three stereocenters depending on the starting ketones. This...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chinese chemical letters 2022-11, Vol.33 (11), p.4891-4895
Hauptverfasser:	Zeng, Mengting, Xue, Ying, Qin, Yunan, Peng, Fen, Li, Quan, Zeng, Ming-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-tumor activities Biginelli reaction Bridged polyheterocycles Domino reaction Multicomponent reaction Reaction mechanism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!