The marriage of sealant agent between structure transformable silk fibroin and traditional Chinese medicine for faster skin repair

Fast skin repair is critical for less infection, less pain and high quality of life, which is still limited with undesirable rehabilitation speed and side effects. Currently, laser-activated silk sealant agent without suture and gauze has been demonstrated promising for fast skin repair taking advan...

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Veröffentlicht in:Chinese chemical letters 2022-03, Vol.33 (3), p.1599-1603
Hauptverfasser: Zhang, Rongjun, Zheng, Youbin, Liu, Tianqing, Tang, Ning, Mao, Lianzhi, Lin, Lihan, Ye, Jiahui, Xie, Luoyijun, Hu, Wenwen, Wu, Weiwei, Liao, Wenzhen, Yuan, Miaomiao
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container_end_page 1603
container_issue 3
container_start_page 1599
container_title Chinese chemical letters
container_volume 33
creator Zhang, Rongjun
Zheng, Youbin
Liu, Tianqing
Tang, Ning
Mao, Lianzhi
Lin, Lihan
Ye, Jiahui
Xie, Luoyijun
Hu, Wenwen
Wu, Weiwei
Liao, Wenzhen
Yuan, Miaomiao
description Fast skin repair is critical for less infection, less pain and high quality of life, which is still limited with undesirable rehabilitation speed and side effects. Currently, laser-activated silk sealant agent without suture and gauze has been demonstrated promising for fast skin repair taking advantage of its structural transformation after heating. Nevertheless, more efficient healing effects and less side effects of laser-activated silk sealant agent remains challenging due to absence of suitable photo-thermal materials and robust/biomimetic protein materials. In this work, the marriage between silk protein and Rehmanniae radix preparata (a kind of the traditional Chinese herb) has been demonstrated as a novel and effective way to achieve an excellent healing effect for skin repair. The non-toxicity, high photothermal conversion efficiency and healing mechanism are systematically studied and proved. This new methodology might shed a new light for combining dark traditional Chinese medicine and silk fibroin for advanced wound healing technology. [Display omitted] The marriage between silk protein and Rehmanniae radix preparata (a kind of traditional Chinese herb) has been demonstrated as a novel and effective way to achieve an excellent healing effect for skin repair with advantages of non-toxicity and high photothermal conversion efficiency.
doi_str_mv 10.1016/j.cclet.2021.09.018
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Currently, laser-activated silk sealant agent without suture and gauze has been demonstrated promising for fast skin repair taking advantage of its structural transformation after heating. Nevertheless, more efficient healing effects and less side effects of laser-activated silk sealant agent remains challenging due to absence of suitable photo-thermal materials and robust/biomimetic protein materials. In this work, the marriage between silk protein and Rehmanniae radix preparata (a kind of the traditional Chinese herb) has been demonstrated as a novel and effective way to achieve an excellent healing effect for skin repair. The non-toxicity, high photothermal conversion efficiency and healing mechanism are systematically studied and proved. This new methodology might shed a new light for combining dark traditional Chinese medicine and silk fibroin for advanced wound healing technology. [Display omitted] The marriage between silk protein and Rehmanniae radix preparata (a kind of traditional Chinese herb) has been demonstrated as a novel and effective way to achieve an excellent healing effect for skin repair with advantages of non-toxicity and high photothermal conversion efficiency.</description><identifier>ISSN: 1001-8417</identifier><identifier>EISSN: 1878-5964</identifier><identifier>DOI: 10.1016/j.cclet.2021.09.018</identifier><language>eng</language><publisher>Elsevier B.V</publisher><subject>Photo-thermal effect ; Rehmanniae radix preparata ; Sealant agent ; Silk fibroin ; Skin repair</subject><ispartof>Chinese chemical letters, 2022-03, Vol.33 (3), p.1599-1603</ispartof><rights>2021</rights><rights>Copyright © Wanfang Data Co. Ltd. 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Currently, laser-activated silk sealant agent without suture and gauze has been demonstrated promising for fast skin repair taking advantage of its structural transformation after heating. Nevertheless, more efficient healing effects and less side effects of laser-activated silk sealant agent remains challenging due to absence of suitable photo-thermal materials and robust/biomimetic protein materials. In this work, the marriage between silk protein and Rehmanniae radix preparata (a kind of the traditional Chinese herb) has been demonstrated as a novel and effective way to achieve an excellent healing effect for skin repair. The non-toxicity, high photothermal conversion efficiency and healing mechanism are systematically studied and proved. This new methodology might shed a new light for combining dark traditional Chinese medicine and silk fibroin for advanced wound healing technology. 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source Elsevier ScienceDirect Journals Complete; Alma/SFX Local Collection
subjects Photo-thermal effect
Rehmanniae radix preparata
Sealant agent
Silk fibroin
Skin repair
title The marriage of sealant agent between structure transformable silk fibroin and traditional Chinese medicine for faster skin repair
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