Enhancing the immune response and tumor suppression effect of antitumor vaccines adjuvanted with non-nucleotide small molecule STING agonist

We constructed an antitumor vaccine by physical mixing novel non-nucleotide small molecule STING agonist diABZI with a glycopeptide antigen. Immunological evaluation indicated diABZI not only enhanced the production of antibodies and T cell immune responses, but also inhibited tumor growth in tumor-...

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Veröffentlicht in:	Chinese chemical letters 2021-06, Vol.32 (6), p.1888-1892
Hauptverfasser:	Wang, Zhaoyu, Chen, Qiang, Zhu, Haomiao, Yin, Xiaona, Wang, Kun, Liu, Yonghui, Zhao, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer vaccine Glycopeptide MUC1 antigen STING Vaccine adjuvant
Online-Zugang:	Volltext
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