Optical monitoring the degradation of PLGA inverse opal film

Implantable materials have broad applications in tissue engineering and in vivo sensors. It is essential to know the detailed information of the implantable materials during their degradation. In this paper, we developed a method to monitor the degradation process of a well-used biomaterial, poly(la...

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Veröffentlicht in:Chinese chemical letters 2013, Vol.24 (1), p.9-12
Hauptverfasser: Sun, Li-Guo, Xie, Zhuo-Ying, Zhao, Yuan-Jin, Wei, Hong-Mei, Gu, Zhong-Ze
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container_issue 1
container_start_page 9
container_title Chinese chemical letters
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creator Sun, Li-Guo
Xie, Zhuo-Ying
Zhao, Yuan-Jin
Wei, Hong-Mei
Gu, Zhong-Ze
description Implantable materials have broad applications in tissue engineering and in vivo sensors. It is essential to know the detailed information of the implantable materials during their degradation. In this paper, we developed a method to monitor the degradation process of a well-used biomaterial, poly(lactide-co- glycolide) (PLGA) by taking advantage of inverse opal structure. We found that mass loss, molecular weight and glass transition temperature of PLGA during the degradation process in Hank's artificial body fluid can be in situ monitored bv measuring the ootical orooerties of PLGA inverse ooal.
doi_str_mv 10.1016/j.cclet.2013.01.012
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source Elsevier ScienceDirect Journals; Alma/SFX Local Collection
subjects Degradation
Optical monitoring
PLGA
PLGA inverse opal
光学监测
反蛋白石结构
植入材料
玻璃化转变温度
组织工程
薄膜
降解过程
title Optical monitoring the degradation of PLGA inverse opal film
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