Synthesis of mono-substituted derivatives of 6-aminoquinoline

Several 6-aminoquinoline derivatives,which could be used in drug design,have been synthesized.The reaction conditions were comparatively studied,and the p-chloroaniline was used as optimum oxidant in Skraup-Doebner-Von Miller reaction.The nitro group was reduced effectively by SnCl2 with no halo-rem...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chinese chemical letters 2011-03, Vol.22 (3), p.253-255
Hauptverfasser:	Lan, Tian, Yuan, Xian Xia, Yu, Jiang Hong, Jia, Chao, Wang, Yu Shi, Zhang, Hui Juan, Ma, Zi Feng, Ye, Wei Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Aminoquinoline 6-Nitroquinoline Oxidant Skraup reaction 单取代 反应条件 喹啉衍生物 氯化亚锡 氯苯胺 药物设计
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!