A new compound from the fruit of Amorpha fruticosa and activity against acetaminophen-induced hepatotoxicity

A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran-12-one,1,4,10,11-tetrahydro-6′-[8′-(hydroxymethyl)ethenyl]-2,3-dimethoxy-8′-O-β- d-glucopyranosyl-O-α- d-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And t...

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Veröffentlicht in:Chinese chemical letters 2009-08, Vol.20 (8), p.942-944
Hauptverfasser: Diao, Yun Peng, Li, Kun, Huang, Shan Shan, Liu, Ke Xin, Kang, Ting Guo
Format: Artikel
Sprache:eng
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Zusammenfassung:A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran-12-one,1,4,10,11-tetrahydro-6′-[8′-(hydroxymethyl)ethenyl]-2,3-dimethoxy-8′-O-β- d-glucopyranosyl-O-α- d-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And the activity against acetaminophen-induced hepatotoxicity of this compound was also studied, and found this compound can protect liver obviously from hepatotoxicity induced by acetaminophen (AAP).
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2009.03.039