Numerical simulation of magnetic drug targeting with Eulerian-Lagrangian model and effect of viscosity modification due to diabetics
The targeted drug delivery and targeted drug therapy transport a drug directly to the center of the disease under various conditions and thereby treat it deliber- ately without effects on the body. This paper studies the magnetic drug targeting （MDT） technique by particle tracking in the presence of...
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| Veröffentlicht in: | Applied mathematics and mechanics 2016-12, Vol.37 (12), p.1631-1646 |
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| container_title | Applied mathematics and mechanics |
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| creator | Larimi, M. M. Ramiar, A. Ranjbar, A. A. |
| description | The targeted drug delivery and targeted drug therapy transport a drug directly to the center of the disease under various conditions and thereby treat it deliber- ately without effects on the body. This paper studies the magnetic drug targeting （MDT） technique by particle tracking in the presence of magnetic field in bifurcation vessels of a healthy person and a diabetes patient. The Lagrangian particle tracking is performed to estimate particle behavior under effects of imposed magnetic field gradients along the bifurcation. The results show that the magnetic field increases the volume fraction of particle in the target region, and the efficiency of MDT on a patient with the diabetes disease is better than a healthy person. Also, for the higher magnetic numbers, the flow in the upper branch is strongly affected by the magnetic field. |
| doi_str_mv | 10.1007/s10483-016-2145-8 |
| format | Article |
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M. ; Ramiar, A. ; Ranjbar, A. A.</creator><creatorcontrib>Larimi, M. M. ; Ramiar, A. ; Ranjbar, A. A.</creatorcontrib><description>The targeted drug delivery and targeted drug therapy transport a drug directly to the center of the disease under various conditions and thereby treat it deliber- ately without effects on the body. This paper studies the magnetic drug targeting （MDT） technique by particle tracking in the presence of magnetic field in bifurcation vessels of a healthy person and a diabetes patient. The Lagrangian particle tracking is performed to estimate particle behavior under effects of imposed magnetic field gradients along the bifurcation. The results show that the magnetic field increases the volume fraction of particle in the target region, and the efficiency of MDT on a patient with the diabetes disease is better than a healthy person. 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The results show that the magnetic field increases the volume fraction of particle in the target region, and the efficiency of MDT on a patient with the diabetes disease is better than a healthy person. 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| source | Springer Nature - Complete Springer Journals; Alma/SFX Local Collection |
| subjects | Applications of Mathematics Classical Mechanics Concentration (composition) Fluid- and Aerodynamics Mathematical Modeling and Industrial Mathematics Mathematics Mathematics and Statistics Partial Differential Equations |
| title | Numerical simulation of magnetic drug targeting with Eulerian-Lagrangian model and effect of viscosity modification due to diabetics |
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