Neuroprotective effect of pAkt and HIF-1α on ischemia rats

Objective:To explore the neuroprotective effect of pAkt and HIF-1α011 ischemia rats.Methods:The rat model of cerebral ischemia which induced by permanent middle cerebral artery occlusion was established.Silybin were given respectively.The behavior was measured by modified Longa method,brain water co...

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Veröffentlicht in:	Asian Pacific journal of tropical medicine 2014-03, Vol.7 (3), p.221-225
Hauptverfasser:	Liu, Bao-Nan, Han, Bo-Xiang, Liu, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - metabolism Body Water - drug effects Body Water - metabolism Brain Chemistry - drug effects Brain Infarction - metabolism Brain Ischemia HIF-1 α HIF-1α Hypoxia-Inducible Factor 1, alpha Subunit - genetics Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Ischemia Male Neuroprotection Neuroprotective Agents - pharmacology NF-kappa B - genetics NF-kappa B - metabolism pAkt Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Rats Rats, Sprague-Dawley Silymarin - pharmacology
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