Developmental systems biology flourishing on new technologies

Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational an...

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Veröffentlicht in:Journal of genetics and genomics 2008-10, Vol.35 (10), p.577-584
Hauptverfasser: Han, Jing-Dong J., Liu, Yi, Xue, Huiling, Xia, Kai, Yu, Hong, Zhu, Shanshan, Chen, Zhang, Zhang, Wei, Huang, Zheng, Jin, Chunyu, Xian, Bo, Li, Jing, Hou, Lei, Han, Yixing, Niu, Chaoqun, Alcon, Timothy C.
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container_end_page 584
container_issue 10
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container_title Journal of genetics and genomics
container_volume 35
creator Han, Jing-Dong J.
Liu, Yi
Xue, Huiling
Xia, Kai
Yu, Hong
Zhu, Shanshan
Chen, Zhang
Zhang, Wei
Huang, Zheng
Jin, Chunyu
Xian, Bo
Li, Jing
Hou, Lei
Han, Yixing
Niu, Chaoqun
Alcon, Timothy C.
description Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational and modeling approaches have opened new frontiers for both systems biologists and developmental biologists to reexamine the old developmental biology questions, such as pattern formation, and to tackle new problems, such as stem cell reprogramming. As showcased in the International Developmental Systems Biology Symposium organized by Chinese Academy of Sciences, developmental systems biology is flourishing in many perspectives, from the evolution of developmental systems, to the underlying genetic and molecular pathways and networks, to the genomic, epigenomic and noncoding levels, to the computational analysis and modeling. We believe that the field will continue to reap rewards into the future with these new approaches.
doi_str_mv 10.1016/S1673-8527(08)60078-8
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subjects Animals
Computational Biology
Developmental Biology - methods
developmental systems biology
Epigenesis, Genetic
Evolution, Molecular
Genomics
Humans
new technologies
RNA, Untranslated - genetics
RNA, Untranslated - metabolism
symposium
Systems Biology - methods
title Developmental systems biology flourishing on new technologies
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