The intracellular mechanism of alpha-fetoprotein promoting the proliferation of NIH 3T3 cells

The existence and properties of alpha-fetoprotein (AFP) receptor on the surface of NIH 3T3 cells and the effects of AFP on cellular signal transduction pathway were investigated. The effect of AFP on the proliferation of NIH 3T3 cells was measured by incorporation of 3H-TdR. Receptor-binding assay o...

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Veröffentlicht in:	Cell research 2002-06, Vol.12 (2), p.151-156
Hauptverfasser:	Li, Meng Sen, Li, Ping Feng, Yang, Fei Yi, He, Shi Peng, Du, Guo Guang, Li, Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells alpha-Fetoproteins - metabolism alpha-Fetoproteins - physiology Animals Cell Division Cyclic AMP - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism Dose-Response Relationship, Drug Humans Mice Receptors, Peptide - metabolism Signal Transduction Time Factors
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