经股动脉留置导管肝动脉灌注化疗联合微量泵持续灌注5-Fu治疗肝转移瘤疗效观察
目的 探讨经股动脉留置导管肝动脉灌注化疗联合微量泵持续灌注5-Fu治疗肝转移瘤的临床疗效及应用价值.方法 58例肝转移瘤患者,根据治疗方式不同分为2组：治疗组33例,采用肝动脉插管灌注化疗,术后肝动脉内留置导管应用微量泵持续72h灌注5-Fu,并联合亚叶酸钙静滴辅助化疗;对照组25例,采用单纯肝动脉插管灌注化疗.两组患者均治疗2个疗程,术后随访有效率、临床受益率、生存时间等指标.结果 治疗组、对照组有效率分别为69.7%,40.0%（P〈0.05）;治疗组术后6,12,24个月生存率为93.4%,72.7%,45.5%,对照组分别为80.8%,44.0%,12.0%（P〈0.05）;治疗组临床...
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| Veröffentlicht in: | 潍坊医学院学报 2012, Vol.34 (2), p.81-83 |
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| container_title | 潍坊医学院学报 |
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| creator | 张兆光 赵荣荣 赵瑶 张仕状 |
| description | 目的 探讨经股动脉留置导管肝动脉灌注化疗联合微量泵持续灌注5-Fu治疗肝转移瘤的临床疗效及应用价值.方法 58例肝转移瘤患者,根据治疗方式不同分为2组：治疗组33例,采用肝动脉插管灌注化疗,术后肝动脉内留置导管应用微量泵持续72h灌注5-Fu,并联合亚叶酸钙静滴辅助化疗;对照组25例,采用单纯肝动脉插管灌注化疗.两组患者均治疗2个疗程,术后随访有效率、临床受益率、生存时间等指标.结果 治疗组、对照组有效率分别为69.7%,40.0%（P〈0.05）;治疗组术后6,12,24个月生存率为93.4%,72.7%,45.5%,对照组分别为80.8%,44.0%,12.0%（P〈0.05）;治疗组临床受益率明显高于对照组.结论 肝动脉内灌注化疗联合肝动脉内留置导管经微量泵持续灌注5-Fu较单纯肝动脉灌注化疗临床受益率高、生存时间长,值得临床应用推广. |
| doi_str_mv | 10.3969/j.issn.1004-3101.2012.02.001 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1004-3101 |
| ispartof | 潍坊医学院学报, 2012, Vol.34 (2), p.81-83 |
| issn | 1004-3101 |
| language | chi |
| recordid | cdi_wanfang_journals_wfyxyxb201202001 |
| source | Alma/SFX Local Collection |
| subjects | 5-Fu 微量泵 持续灌注 留置导管 肝转移瘤 股动脉 |
| title | 经股动脉留置导管肝动脉灌注化疗联合微量泵持续灌注5-Fu治疗肝转移瘤疗效观察 |
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