氘氚标记治疗老年性痴呆症药物zt-1

TQ463.7%O613.2; 用钠硼氘、钠硼氚还原5-氯-邻香草醛制备氘标记、氘标记5-氯-邻香草醛,然后与石杉碱甲在避光条件下缩合生成氘标记、氚标记zt-1.经硅胶板层析所得Rf与zt-1标准品的一致,经紫外检测其λmax=303nm也与标准品的一致.氚标记zt-1的放化纯度>95%,放射性比活度为401.3 GBq/g....

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Veröffentlicht in:同位素 2003, Vol.16 (3), p.197-211
Hauptverfasser: 吴元芳, 李惠源, 董墨
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container_title 同位素
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creator 吴元芳
李惠源
董墨
description TQ463.7%O613.2; 用钠硼氘、钠硼氚还原5-氯-邻香草醛制备氘标记、氘标记5-氯-邻香草醛,然后与石杉碱甲在避光条件下缩合生成氘标记、氚标记zt-1.经硅胶板层析所得Rf与zt-1标准品的一致,经紫外检测其λmax=303nm也与标准品的一致.氚标记zt-1的放化纯度>95%,放射性比活度为401.3 GBq/g.
doi_str_mv 10.3969/j.issn.1000-7512.2003.03.016
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