LRP6 Bidirectionally Regulates Insulin Sensitivity through Insulin Receptor and S6K Signaling in Rats with CG-IUGR

Objective Intrauterine growth restriction followed by postnatal catch-up growth (CG-IUGR) increases the risk of insulin resistance-related diseases. Low-density lipoprotein receptor-related protein 6 (LRP6) plays a substantial role in glucose metabolism. However, whether LRP6 is involved in the insu...

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Veröffentlicht in:Current medical science 2023-04, Vol.43 (2), p.274-283
Hauptverfasser: Xie, Xue-mei, Cao, Qiu-li, Sun, Yu-jie, Zhang, Jie, Liu, Kai-li, Qin, Ying-fen, Long, Wen-jun, Luo, Zuo-jie, Li, Xiao-wei, Liang, Xing-huan, Yuan, Guan-dou, Luo, Xiao-ping, Xuan, Xiu-ping
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Sprache:eng
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