Angiogenic Factors Are Associated with Development of Acute Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Acute graft-versus-host disease（a GVHD） is a serious complication after allogeneic hematopoietic stem cell transplantation（allo-HSCT）. However,the mechanisms of a GVHD are not well understood. We aim to investigate the roles of the three angiogenic factors： angiopoietin-1（Ang-1）,Ang-2 and vascular e...

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Veröffentlicht in:	Journal of Huazhong University of Science and Technology. Medical sciences 2015-10, Vol.35 (5), p.694-699
1. Verfasser:	聂第敏吴秋玲朱夏夏张然郑鹏方俊游泳仲照东夏凌辉洪梅
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Angiogenesis Inducing Agents - immunology Angiogenesis Inducing Agents - metabolism Angiogenesis Inducing Agents - pharmacology Angiopoietin-1 - genetics Angiopoietin-1 - immunology Angiopoietin-1 - pharmacology Angiopoietin-2 - genetics Angiopoietin-2 - immunology Angiopoietin-2 - pharmacology Antineoplastic Agents - therapeutic use Female Gene Expression Regulation, Neoplastic Graft vs Host Disease - genetics Graft vs Host Disease - immunology Graft vs Host Disease - pathology Hematopoietic Stem Cell Transplantation Human Umbilical Vein Endothelial Cells - cytology Human Umbilical Vein Endothelial Cells - drug effects Human Umbilical Vein Endothelial Cells - immunology Humans Leukemia, Myeloid - genetics Leukemia, Myeloid - immunology Leukemia, Myeloid - pathology Leukemia, Myeloid - therapy Lymphoma, Non-Hodgkin - genetics Lymphoma, Non-Hodgkin - immunology Lymphoma, Non-Hodgkin - pathology Lymphoma, Non-Hodgkin - therapy Male Medicine Medicine & Public Health Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Retrospective Studies Signal Transduction Transplantation, Homologous Tumor Necrosis Factor-alpha - pharmacology Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - immunology VEGF 内皮细胞异基因造血干细胞移植急性移植物抗宿主病肿瘤坏死因子-α 血管内皮生长因子血管生成因子
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