In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate
Summary： The purpose of the present study was to observe the structure and functional change of the bone-coating-prosthesis interface in vivo and to evaluate the histocompatibility of self-made prosthetic femoral components in the body and the degree of their bonding with the surrounding bone tissue...
Gespeichert in:
| Veröffentlicht in: | Journal of Huazhong University of Science and Technology. Medical sciences 2013-08, Vol.33 (4), p.543-550 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 550 |
|---|---|
| container_issue | 4 |
| container_start_page | 543 |
| container_title | Journal of Huazhong University of Science and Technology. Medical sciences |
| container_volume | 33 |
| creator | Zeng, Xian-lin Li, Jing-feng Yang, Shu-hua Zheng, Qi-xin Zou, Zhen-wei |
| description | Summary： The purpose of the present study was to observe the structure and functional change of the bone-coating-prosthesis interface in vivo and to evaluate the histocompatibility of self-made prosthetic femoral components in the body and the degree of their bonding with the surrounding bone tissues as well as their stability. Six mature beagle dogs underwent bilateral hip replacement with prosthetic femur components. Three groups were established in terms of different coating of prothesis （four joints in each group）： atmosphere （A） plasma-sprayed pure titanium （Ti） prosthetic joint with hydroxyapatite （HA） coating （HA＋Ti＋A group）; vacuum （V） plasma-sprayed pure Ti prosthetic joint with HA coating （HA＋Ti＋V group）; vacuum plasma-sprayed pure Ti prosthetic joint with Ti-HA stepped coating （Ti＋HAG＋Ti＋V group）. The hip joints were functionally evaluated, and subjected to X-ray examination, biomechanics inspection, and histological examination. As a result, X-ray imaging revealed all prosthetic joints were in a good location and no dislocation of joint was found. Shear strength of interface was significantly higher in Ti＋HAG＋Ti＋V group than in HA＋Ti＋V group （P〈0.05） and HA＋Ti＋A group （P〈0.05） at 28th week. Histological examination showed the amount of newborn bone in Ti＋HAG＋Ti＋V group was more than in HA＋Ti＋V group and HA＋Ti＋A group after 28 weeks. It was suggested that vacuum plasma-sprayed pure Ti prosthetic joint with TI-HA stepped coating could improve the bonding capacity of bone-prosthesis, enhance the stability of prosthesis, and increase the fixion of prosthetic femoral components because of better bone growth. This new type of biological material in prosthetic femoral components holds promises for application in clinical practice. |
| doi_str_mv | 10.1007/s11596-013-1156-1 |
| format | Article |
| fullrecord | <record><control><sourceid>wanfang_jour_proqu</sourceid><recordid>TN_cdi_wanfang_journals_tjykdxxb_e201304015</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>46599936</cqvip_id><wanfj_id>tjykdxxb_e201304015</wanfj_id><sourcerecordid>tjykdxxb_e201304015</sourcerecordid><originalsourceid>FETCH-LOGICAL-c358t-940c999b73b6e948b0073a7f0b471f8042c4856b453e8bdceff8f06c4a2b05793</originalsourceid><addsrcrecordid>eNp9kUFv1DAQhSMEoqXwA7ggc0NCBju24_hYrSittBKVWLhaduLsZkns1HbarsSPZ1ZZyo2Tx9I3b2beK4q3lHyihMjPiVKhKkwow1BVmD4rzqlS8GOifA51JUtMJGNnxauU9oQIWZX8ZXFWMkU4k-K8-H3j0c_-PqCNS7n3WxQ6tDK-9w7dxpDyzuW-QVduDNEMaBXGKXjnc0IPfd6h60u86dHatK2LOB8mB4RZZEDWNPM8otvBpNHgNEVzcC0C_vtsU44mu9fFi84Myb05vRfFj6svm9U1Xn_7erO6XOOGiTpjxUmjlLKS2copXlu4nRnZEcsl7WrCy4bXorJcMFfbtnFdV3ekargpLZys2EXxcdF9ML4zfqv3YY4eJuq8P_xqHx-tdiW4SDihAugPCz3FcDeDLXrsU-OGwXgX5qQpp1KUspYUULqgDXiVouv0FPvRxIOmRB8j0ktEGsT1MSJ97Hl3kp_t6Nqnjr-ZAFAuAFgGVrr4b93_qb4_bbILfnsHfU_CvBLgHqvYHwqppt0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1417527871</pqid></control><display><type>article</type><title>In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Zeng, Xian-lin ; Li, Jing-feng ; Yang, Shu-hua ; Zheng, Qi-xin ; Zou, Zhen-wei</creator><creatorcontrib>Zeng, Xian-lin ; Li, Jing-feng ; Yang, Shu-hua ; Zheng, Qi-xin ; Zou, Zhen-wei</creatorcontrib><description>Summary： The purpose of the present study was to observe the structure and functional change of the bone-coating-prosthesis interface in vivo and to evaluate the histocompatibility of self-made prosthetic femoral components in the body and the degree of their bonding with the surrounding bone tissues as well as their stability. Six mature beagle dogs underwent bilateral hip replacement with prosthetic femur components. Three groups were established in terms of different coating of prothesis （four joints in each group）： atmosphere （A） plasma-sprayed pure titanium （Ti） prosthetic joint with hydroxyapatite （HA） coating （HA＋Ti＋A group）; vacuum （V） plasma-sprayed pure Ti prosthetic joint with HA coating （HA＋Ti＋V group）; vacuum plasma-sprayed pure Ti prosthetic joint with Ti-HA stepped coating （Ti＋HAG＋Ti＋V group）. The hip joints were functionally evaluated, and subjected to X-ray examination, biomechanics inspection, and histological examination. As a result, X-ray imaging revealed all prosthetic joints were in a good location and no dislocation of joint was found. Shear strength of interface was significantly higher in Ti＋HAG＋Ti＋V group than in HA＋Ti＋V group （P〈0.05） and HA＋Ti＋A group （P〈0.05） at 28th week. Histological examination showed the amount of newborn bone in Ti＋HAG＋Ti＋V group was more than in HA＋Ti＋V group and HA＋Ti＋A group after 28 weeks. It was suggested that vacuum plasma-sprayed pure Ti prosthetic joint with TI-HA stepped coating could improve the bonding capacity of bone-prosthesis, enhance the stability of prosthesis, and increase the fixion of prosthetic femoral components because of better bone growth. This new type of biological material in prosthetic femoral components holds promises for application in clinical practice.</description><identifier>ISSN: 1672-0733</identifier><identifier>EISSN: 1993-1352</identifier><identifier>DOI: 10.1007/s11596-013-1156-1</identifier><identifier>PMID: 23904375</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Animals ; Biomechanical Phenomena - drug effects ; Biomechanical Phenomena - physiology ; Bone Development - drug effects ; Bone Development - physiology ; Coated Materials, Biocompatible - pharmacology ; Dogs ; Durapatite - pharmacology ; Femur - drug effects ; Femur - physiology ; HA涂层 ; Medicine ; Medicine & Public Health ; Prostheses and Implants ; Titanium - pharmacology ; Vacuum ; 人工关节 ; 体内试验 ; 假体 ; 比格犬 ; 真空等离子喷涂 ; 股骨 ; 钛基</subject><ispartof>Journal of Huazhong University of Science and Technology. Medical sciences, 2013-08, Vol.33 (4), p.543-550</ispartof><rights>Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 2013</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c358t-940c999b73b6e948b0073a7f0b471f8042c4856b453e8bdceff8f06c4a2b05793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85740A/85740A.jpg</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23904375$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zeng, Xian-lin</creatorcontrib><creatorcontrib>Li, Jing-feng</creatorcontrib><creatorcontrib>Yang, Shu-hua</creatorcontrib><creatorcontrib>Zheng, Qi-xin</creatorcontrib><creatorcontrib>Zou, Zhen-wei</creatorcontrib><title>In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate</title><title>Journal of Huazhong University of Science and Technology. Medical sciences</title><addtitle>J. Huazhong Univ. Sci. Technol. [Med. Sci.]</addtitle><addtitle>Journal of Zuazhong University of Science and Technology： Medical Edition</addtitle><description>Summary： The purpose of the present study was to observe the structure and functional change of the bone-coating-prosthesis interface in vivo and to evaluate the histocompatibility of self-made prosthetic femoral components in the body and the degree of their bonding with the surrounding bone tissues as well as their stability. Six mature beagle dogs underwent bilateral hip replacement with prosthetic femur components. Three groups were established in terms of different coating of prothesis （four joints in each group）： atmosphere （A） plasma-sprayed pure titanium （Ti） prosthetic joint with hydroxyapatite （HA） coating （HA＋Ti＋A group）; vacuum （V） plasma-sprayed pure Ti prosthetic joint with HA coating （HA＋Ti＋V group）; vacuum plasma-sprayed pure Ti prosthetic joint with Ti-HA stepped coating （Ti＋HAG＋Ti＋V group）. The hip joints were functionally evaluated, and subjected to X-ray examination, biomechanics inspection, and histological examination. As a result, X-ray imaging revealed all prosthetic joints were in a good location and no dislocation of joint was found. Shear strength of interface was significantly higher in Ti＋HAG＋Ti＋V group than in HA＋Ti＋V group （P〈0.05） and HA＋Ti＋A group （P〈0.05） at 28th week. Histological examination showed the amount of newborn bone in Ti＋HAG＋Ti＋V group was more than in HA＋Ti＋V group and HA＋Ti＋A group after 28 weeks. It was suggested that vacuum plasma-sprayed pure Ti prosthetic joint with TI-HA stepped coating could improve the bonding capacity of bone-prosthesis, enhance the stability of prosthesis, and increase the fixion of prosthetic femoral components because of better bone growth. This new type of biological material in prosthetic femoral components holds promises for application in clinical practice.</description><subject>Animals</subject><subject>Biomechanical Phenomena - drug effects</subject><subject>Biomechanical Phenomena - physiology</subject><subject>Bone Development - drug effects</subject><subject>Bone Development - physiology</subject><subject>Coated Materials, Biocompatible - pharmacology</subject><subject>Dogs</subject><subject>Durapatite - pharmacology</subject><subject>Femur - drug effects</subject><subject>Femur - physiology</subject><subject>HA涂层</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Prostheses and Implants</subject><subject>Titanium - pharmacology</subject><subject>Vacuum</subject><subject>人工关节</subject><subject>体内试验</subject><subject>假体</subject><subject>比格犬</subject><subject>真空等离子喷涂</subject><subject>股骨</subject><subject>钛基</subject><issn>1672-0733</issn><issn>1993-1352</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFv1DAQhSMEoqXwA7ggc0NCBju24_hYrSittBKVWLhaduLsZkns1HbarsSPZ1ZZyo2Tx9I3b2beK4q3lHyihMjPiVKhKkwow1BVmD4rzqlS8GOifA51JUtMJGNnxauU9oQIWZX8ZXFWMkU4k-K8-H3j0c_-PqCNS7n3WxQ6tDK-9w7dxpDyzuW-QVduDNEMaBXGKXjnc0IPfd6h60u86dHatK2LOB8mB4RZZEDWNPM8otvBpNHgNEVzcC0C_vtsU44mu9fFi84Myb05vRfFj6svm9U1Xn_7erO6XOOGiTpjxUmjlLKS2copXlu4nRnZEcsl7WrCy4bXorJcMFfbtnFdV3ekargpLZys2EXxcdF9ML4zfqv3YY4eJuq8P_xqHx-tdiW4SDihAugPCz3FcDeDLXrsU-OGwXgX5qQpp1KUspYUULqgDXiVouv0FPvRxIOmRB8j0ktEGsT1MSJ97Hl3kp_t6Nqnjr-ZAFAuAFgGVrr4b93_qb4_bbILfnsHfU_CvBLgHqvYHwqppt0</recordid><startdate>20130801</startdate><enddate>20130801</enddate><creator>Zeng, Xian-lin</creator><creator>Li, Jing-feng</creator><creator>Yang, Shu-hua</creator><creator>Zheng, Qi-xin</creator><creator>Zou, Zhen-wei</creator><general>Springer Berlin Heidelberg</general><general>Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China</general><general>Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China%Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20130801</creationdate><title>In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate</title><author>Zeng, Xian-lin ; Li, Jing-feng ; Yang, Shu-hua ; Zheng, Qi-xin ; Zou, Zhen-wei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c358t-940c999b73b6e948b0073a7f0b471f8042c4856b453e8bdceff8f06c4a2b05793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Animals</topic><topic>Biomechanical Phenomena - drug effects</topic><topic>Biomechanical Phenomena - physiology</topic><topic>Bone Development - drug effects</topic><topic>Bone Development - physiology</topic><topic>Coated Materials, Biocompatible - pharmacology</topic><topic>Dogs</topic><topic>Durapatite - pharmacology</topic><topic>Femur - drug effects</topic><topic>Femur - physiology</topic><topic>HA涂层</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Prostheses and Implants</topic><topic>Titanium - pharmacology</topic><topic>Vacuum</topic><topic>人工关节</topic><topic>体内试验</topic><topic>假体</topic><topic>比格犬</topic><topic>真空等离子喷涂</topic><topic>股骨</topic><topic>钛基</topic><toplevel>online_resources</toplevel><creatorcontrib>Zeng, Xian-lin</creatorcontrib><creatorcontrib>Li, Jing-feng</creatorcontrib><creatorcontrib>Yang, Shu-hua</creatorcontrib><creatorcontrib>Zheng, Qi-xin</creatorcontrib><creatorcontrib>Zou, Zhen-wei</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Journal of Huazhong University of Science and Technology. Medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zeng, Xian-lin</au><au>Li, Jing-feng</au><au>Yang, Shu-hua</au><au>Zheng, Qi-xin</au><au>Zou, Zhen-wei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate</atitle><jtitle>Journal of Huazhong University of Science and Technology. Medical sciences</jtitle><stitle>J. Huazhong Univ. Sci. Technol. [Med. Sci.]</stitle><addtitle>Journal of Zuazhong University of Science and Technology： Medical Edition</addtitle><date>2013-08-01</date><risdate>2013</risdate><volume>33</volume><issue>4</issue><spage>543</spage><epage>550</epage><pages>543-550</pages><issn>1672-0733</issn><eissn>1993-1352</eissn><abstract>Summary： The purpose of the present study was to observe the structure and functional change of the bone-coating-prosthesis interface in vivo and to evaluate the histocompatibility of self-made prosthetic femoral components in the body and the degree of their bonding with the surrounding bone tissues as well as their stability. Six mature beagle dogs underwent bilateral hip replacement with prosthetic femur components. Three groups were established in terms of different coating of prothesis （four joints in each group）： atmosphere （A） plasma-sprayed pure titanium （Ti） prosthetic joint with hydroxyapatite （HA） coating （HA＋Ti＋A group）; vacuum （V） plasma-sprayed pure Ti prosthetic joint with HA coating （HA＋Ti＋V group）; vacuum plasma-sprayed pure Ti prosthetic joint with Ti-HA stepped coating （Ti＋HAG＋Ti＋V group）. The hip joints were functionally evaluated, and subjected to X-ray examination, biomechanics inspection, and histological examination. As a result, X-ray imaging revealed all prosthetic joints were in a good location and no dislocation of joint was found. Shear strength of interface was significantly higher in Ti＋HAG＋Ti＋V group than in HA＋Ti＋V group （P〈0.05） and HA＋Ti＋A group （P〈0.05） at 28th week. Histological examination showed the amount of newborn bone in Ti＋HAG＋Ti＋V group was more than in HA＋Ti＋V group and HA＋Ti＋A group after 28 weeks. It was suggested that vacuum plasma-sprayed pure Ti prosthetic joint with TI-HA stepped coating could improve the bonding capacity of bone-prosthesis, enhance the stability of prosthesis, and increase the fixion of prosthetic femoral components because of better bone growth. This new type of biological material in prosthetic femoral components holds promises for application in clinical practice.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23904375</pmid><doi>10.1007/s11596-013-1156-1</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1672-0733 |
| ispartof | Journal of Huazhong University of Science and Technology. Medical sciences, 2013-08, Vol.33 (4), p.543-550 |
| issn | 1672-0733 1993-1352 |
| language | eng |
| recordid | cdi_wanfang_journals_tjykdxxb_e201304015 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Biomechanical Phenomena - drug effects Biomechanical Phenomena - physiology Bone Development - drug effects Bone Development - physiology Coated Materials, Biocompatible - pharmacology Dogs Durapatite - pharmacology Femur - drug effects Femur - physiology HA涂层 Medicine Medicine & Public Health Prostheses and Implants Titanium - pharmacology Vacuum 人工关节 体内试验 假体 比格犬 真空等离子喷涂 股骨 钛基 |
| title | In Vivo Testing of Canine Prosthetic Femoral Components with HA-Ti Ladder-type Coating on Vacuum Plasma-sprayed Ti Substrate |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T10%3A35%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wanfang_jour_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20Vivo%20Testing%20of%20Canine%20Prosthetic%20Femoral%20Components%20with%20HA-Ti%20Ladder-type%20Coating%20on%20Vacuum%20Plasma-sprayed%20Ti%20Substrate&rft.jtitle=Journal%20of%20Huazhong%20University%20of%20Science%20and%20Technology.%20Medical%20sciences&rft.au=Zeng,%20Xian-lin&rft.date=2013-08-01&rft.volume=33&rft.issue=4&rft.spage=543&rft.epage=550&rft.pages=543-550&rft.issn=1672-0733&rft.eissn=1993-1352&rft_id=info:doi/10.1007/s11596-013-1156-1&rft_dat=%3Cwanfang_jour_proqu%3Etjykdxxb_e201304015%3C/wanfang_jour_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1417527871&rft_id=info:pmid/23904375&rft_cqvip_id=46599936&rft_wanfj_id=tjykdxxb_e201304015&rfr_iscdi=true |