Effects of RNAi-mediated Gene Silencing of LRIG1 on Proliferation and Invasion of Glioma Cells

The effects of RNAi-mediated gene silencing of LRlG1 on proliferation and invasion of the human glioma cell line U251-MG and the possible mechanisms were explored in this study. The plasmids pGenesil2-LRIG1-shRNA1 and pGenesil2-LRIG1-shRNA2 were transfected into U251-MG glioma cells respectively by...

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Veröffentlicht in:	Journal of Huazhong University of Science and Technology. Medical sciences 2012-04, Vol.32 (2), p.227-232
1. Verfasser:	毛峰王宝峰席桂发孙伟张华楸叶飞郭东生雷霆
Format:	Artikel
Sprache:	eng
Schlagworte:	cell Cell cycle Cell Line, Tumor Cell Proliferation Flow cytometry Gene expression Gene Silencing glioma Glioma - genetics Glioma - pathology Glioma cells Humans invasion LRIG Medicine Medicine & Public Health Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Plasmids proliferation RNA Interference S phase siRNA Transcription Western blotting
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