Chelation of GRP78 with Lead and Its Localization Changes in the Astroglia of Rats Exposed to Lead

To observe the chelation of GRP78 with lead （Pb） and its localization changes, astroglial ceils from Wistar rat brain were primarily cultured in medium witb acetate Pb. The processes were terminated at different time points. The immunoprecipitation （IP） and Western blotting were used for GRP78 purif...

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Veröffentlicht in:	Journal of Huazhong University of Science and Technology. Medical sciences 2009-08, Vol.29 (4), p.492-497
1. Verfasser:	张莹叶丽平王彪李妍孙黎光
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - cytology Cells, Cultured Chelating Agents - metabolism Chelating Agents - pharmacology Environmental Exposure - adverse effects Heat-Shock Proteins - metabolism Heat-Shock Proteins - pharmacology Hippocampus - cytology Lead - pharmacokinetics Lead - toxicity Medicine Medicine & Public Health Rats Rats, Wistar 原子吸收光谱法大鼠脑星形胶质细胞本地化胶体金免疫电镜螯合作用醋酸铅
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