In vitro Acute Cytotoxicity of Abamectin to the Gill Cell Line of Flounder Paralichthy olivaceus

The cytotoxicity of abamectin to the Gill Cell Line of Flounder (FG cell line) was examined in this study. It was found that the exposure of FG cells to abamectin caused the decreases of both cell growth rate and antioxidant enzyme activities, and the increase of intracellular 02 content. It was pro...

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Veröffentlicht in:Journal of Ocean University of China 2007-10, Vol.6 (4), p.369-372
Hauptverfasser: Xu, Yuyan, Guo, Huarong, Xiao, Qin, Su, Feng, Yin, Licheng
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container_title Journal of Ocean University of China
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creator Xu, Yuyan
Guo, Huarong
Xiao, Qin
Su, Feng
Yin, Licheng
description The cytotoxicity of abamectin to the Gill Cell Line of Flounder (FG cell line) was examined in this study. It was found that the exposure of FG cells to abamectin caused the decreases of both cell growth rate and antioxidant enzyme activities, and the increase of intracellular 02 content. It was proposed that the reduction of antioxidant enzyme activities in FG cells caused the accumulation of 02 content in FG cells, leading to the change of cell morphology and even the death of cells. The results showed that FG cell line is suitable for the evaluation of the acute toxicity of abamectin.
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source SpringerNature Journals; Alma/SFX Local Collection
subjects Acute toxicity
Antioxidants
Cell morphology
Cytotoxicity
Enzymatic activity
Enzymes
Fish
Fungicides
Insecticides
Marine
Marine biology
Pleuronectiformes
Studies
抗氧化剂
生命科学
生物学
细胞毒性
title In vitro Acute Cytotoxicity of Abamectin to the Gill Cell Line of Flounder Paralichthy olivaceus
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