2型糖尿病患者血清唾液酸浓度与糖尿病性黄斑水肿的相关性
目的:探讨2型糖尿病患者血清唾液酸浓度与糖尿病性黄斑水肿的相关性。方法:选取65例2型糖尿病患者,以及54例正常对照,采取外周静脉血后用比色法测量血清唾液酸浓度。对于糖尿病患者采用视网膜血管荧光造影方法判断黄斑区水肿程度。结果:糖尿病患者65例中黄斑水肿22例,无黄斑水肿43例,其中1级水肿10例,2级水肿5例,3级水肿7例。糖尿病患者血清唾液酸浓度为96.56±14.29mmol/L,对照组的血清唾液酸浓度为42.44±17.68mmol/L,两组比较有显著统计学差异(P〈0.05)。在糖尿病患者组,无黄斑水肿的患者血清唾液酸浓度为86.53±13.39mmol/L,有黄斑水肿的患者中血清唾...
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description | 目的:探讨2型糖尿病患者血清唾液酸浓度与糖尿病性黄斑水肿的相关性。方法:选取65例2型糖尿病患者,以及54例正常对照,采取外周静脉血后用比色法测量血清唾液酸浓度。对于糖尿病患者采用视网膜血管荧光造影方法判断黄斑区水肿程度。结果:糖尿病患者65例中黄斑水肿22例,无黄斑水肿43例,其中1级水肿10例,2级水肿5例,3级水肿7例。糖尿病患者血清唾液酸浓度为96.56±14.29mmol/L,对照组的血清唾液酸浓度为42.44±17.68mmol/L,两组比较有显著统计学差异(P〈0.05)。在糖尿病患者组,无黄斑水肿的患者血清唾液酸浓度为86.53±13.39mmol/L,有黄斑水肿的患者中血清唾液酸浓度为110.09±18.81mmol/L,两者差异具有统计学意义(P〈0.05)。血清唾液酸浓度与黄斑水肿严重程度有显著正相关(r=0.62,P〈0.05)。结论:血清唾液酸浓度在2型糖尿病患者并发黄斑水肿时明显升高,并且血清唾液酸浓度越高,黄斑水肿越严重。 |
doi_str_mv | 10.3980/j.issn.1672-5123.2016.3.41 |
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subjects | 糖尿病视网膜病变 血清唾液酸 黄斑水肿 |
title | 2型糖尿病患者血清唾液酸浓度与糖尿病性黄斑水肿的相关性 |
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