翼状胬肉组织Caveolin-1,E-cadherin和P63的表达
目的:观察翼状胬肉上皮细胞中caveolin-1,E-cadherin和P63的表达。方法:应用免疫荧光组织化学染色法检测12例翼状胬肉上皮细胞caveolin-1,E-cadherin和P63的表达,并与正常结膜对比。结果:在正常结膜上皮,E-cadherin和P63低表达,caveolin-1无表达。在翼状胬肉组织,E-cadherin和P63的表达明显增强,caveolin-1在上皮基底及基底上部细胞阳性表达。caveolin-1在正常结膜上皮阳性表达的光密度值为0,而在翼状胬肉的吸光度值为9706±2018。E-cadherin和β-catenin在正常结膜与在翼状胬肉的上皮阳性表达的...
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Veröffentlicht in: | Guo ji yan ke za zhi 2009, Vol.9 (11), p.2084-2086 |
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container_title | Guo ji yan ke za zhi |
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creator | 吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃 |
description | 目的:观察翼状胬肉上皮细胞中caveolin-1,E-cadherin和P63的表达。方法:应用免疫荧光组织化学染色法检测12例翼状胬肉上皮细胞caveolin-1,E-cadherin和P63的表达,并与正常结膜对比。结果:在正常结膜上皮,E-cadherin和P63低表达,caveolin-1无表达。在翼状胬肉组织,E-cadherin和P63的表达明显增强,caveolin-1在上皮基底及基底上部细胞阳性表达。caveolin-1在正常结膜上皮阳性表达的光密度值为0,而在翼状胬肉的吸光度值为9706±2018。E-cadherin和β-catenin在正常结膜与在翼状胬肉的上皮阳性表达的吸光度值差异有统计学意义(P〈0.05)。结论:翼状胬肉上皮细胞caveolin-1,E-cadherin和P63蛋白表达异常。 |
doi_str_mv | 10.3969/j.issn.1672-5123.2009.11.013 |
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All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/83813A/83813A.jpg</thumbnail><link.rule.ids>314,780,784,4022,27922,27923,27924</link.rule.ids></links><search><creatorcontrib>吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃</creatorcontrib><title>翼状胬肉组织Caveolin-1,E-cadherin和P63的表达</title><title>Guo ji yan ke za zhi</title><addtitle>International Journal of Ophthalmology</addtitle><description>目的:观察翼状胬肉上皮细胞中caveolin-1,E-cadherin和P63的表达。方法:应用免疫荧光组织化学染色法检测12例翼状胬肉上皮细胞caveolin-1,E-cadherin和P63的表达,并与正常结膜对比。结果:在正常结膜上皮,E-cadherin和P63低表达,caveolin-1无表达。在翼状胬肉组织,E-cadherin和P63的表达明显增强,caveolin-1在上皮基底及基底上部细胞阳性表达。caveolin-1在正常结膜上皮阳性表达的光密度值为0,而在翼状胬肉的吸光度值为9706±2018。E-cadherin和β-catenin在正常结膜与在翼状胬肉的上皮阳性表达的吸光度值差异有统计学意义(P〈0.05)。结论:翼状胬肉上皮细胞caveolin-1,E-cadherin和P63蛋白表达异常。</description><subject>caveolin-1</subject><subject>E-cadherin</subject><subject>P63</subject><subject>上皮</subject><subject>翼状胬肉</subject><issn>1672-5123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNo9jz9Lw0Achm9QsNR-CXERvHi_u-QuN0qof6CgQ_dwSe7SpPGCDSpm1EJRnBzd3BycXSr100jyMYxUnF54eXhfHoR2gThMcnmQO1lVWQe4oNgDyhxKiHQAHAJsA_X--y00qKosIiBcIVzOe4g3X5_N40d7_97ePTTLebNcBOpal0VmMewPcaySiZ5l9vv56Zyz5mXevr61q9U22jSqqPTgL_tofDQcByd4dHZ8GhyOcMyB4YgoUD4YL-Gekdow11MgKAdDDZOCUelKQqiOklh4iZCCEKMjbiJf-EL6gvXR3nr2RlmjbBrm5dXMdofhRZ3mt9O6_hUF6DQ7dmfNxpPSppdZR0cqnpqs0CGjIH0OHvsBsVJgFw</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃</creator><general>厦门大学附属厦门眼科中心,中国福建省厦门市,361005</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>2009</creationdate><title>翼状胬肉组织Caveolin-1,E-cadherin和P63的表达</title><author>吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c613-b0a1a81f5d65f9ef345a17261f2f39732949002ebdc75d79700feb6fb87879873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2009</creationdate><topic>caveolin-1</topic><topic>E-cadherin</topic><topic>P63</topic><topic>上皮</topic><topic>翼状胬肉</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Guo ji yan ke za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>吴护平 董诺 谢素贞 李海波 刘昭升 闫蕾 白琼珍 李东侃</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>翼状胬肉组织Caveolin-1,E-cadherin和P63的表达</atitle><jtitle>Guo ji yan ke za zhi</jtitle><addtitle>International Journal of Ophthalmology</addtitle><date>2009</date><risdate>2009</risdate><volume>9</volume><issue>11</issue><spage>2084</spage><epage>2086</epage><pages>2084-2086</pages><issn>1672-5123</issn><abstract>目的:观察翼状胬肉上皮细胞中caveolin-1,E-cadherin和P63的表达。方法:应用免疫荧光组织化学染色法检测12例翼状胬肉上皮细胞caveolin-1,E-cadherin和P63的表达,并与正常结膜对比。结果:在正常结膜上皮,E-cadherin和P63低表达,caveolin-1无表达。在翼状胬肉组织,E-cadherin和P63的表达明显增强,caveolin-1在上皮基底及基底上部细胞阳性表达。caveolin-1在正常结膜上皮阳性表达的光密度值为0,而在翼状胬肉的吸光度值为9706±2018。E-cadherin和β-catenin在正常结膜与在翼状胬肉的上皮阳性表达的吸光度值差异有统计学意义(P〈0.05)。结论:翼状胬肉上皮细胞caveolin-1,E-cadherin和P63蛋白表达异常。</abstract><pub>厦门大学附属厦门眼科中心,中国福建省厦门市,361005</pub><doi>10.3969/j.issn.1672-5123.2009.11.013</doi><tpages>3</tpages></addata></record> |
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subjects | caveolin-1 E-cadherin P63 上皮 翼状胬肉 |
title | 翼状胬肉组织Caveolin-1,E-cadherin和P63的表达 |
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