急性冠脉综合征患者血清MCP-1浓度和CCR2蛋白表达水平的变化
R541.4; 目的:检测急性冠脉综合征 (acute coronary syndrome, ACS)患者血中单核细胞趋化蛋白-1(monocyte chemotactic protein, MCP-1)和外周血单核细胞MCP-1受体CC趋化因子受体2(CC chemokine receptor 2, CCR2)表达水平的变化,探讨MCP-1和CCR2与ACS发生的关系.方法:收集ACS患者30例和健康体检者30例,分别应用ELISA法和流式细胞技术检测受试者血清MCP-1浓度和单核细胞上CCR2的表达水平.结果:ACS组血清MCP-1的水平明显高于健康对照组(P＜0.05),ACS组外周血单...
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| Veröffentlicht in: | 中南大学学报（医学版） 2009, Vol.34 (4), p.318-322 |
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| container_title | 中南大学学报（医学版） |
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| creator | 汪雁归 刘昭前 杨天(山)/(仑) |
| description | R541.4; 目的:检测急性冠脉综合征 (acute coronary syndrome, ACS)患者血中单核细胞趋化蛋白-1(monocyte chemotactic protein, MCP-1)和外周血单核细胞MCP-1受体CC趋化因子受体2(CC chemokine receptor 2, CCR2)表达水平的变化,探讨MCP-1和CCR2与ACS发生的关系.方法:收集ACS患者30例和健康体检者30例,分别应用ELISA法和流式细胞技术检测受试者血清MCP-1浓度和单核细胞上CCR2的表达水平.结果:ACS组血清MCP-1的水平明显高于健康对照组(P＜0.05),ACS组外周血单核细胞CCR2蛋白表达水平明显高于健康对照组(P＜0.01).结论:ACS患者MCP-1浓度与CCR2表达水平均显著高于健康人,MCP-1和CCR2可能与ACS的发生发展有关. |
| doi_str_mv | 10.3321/j.issn:1672-7347.2009.04.008 |
| format | Article |
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| language | chi |
| recordid | cdi_wanfang_journals_hnykdx200904008 |
| source | Alma/SFX Local Collection |
| title | 急性冠脉综合征患者血清MCP-1浓度和CCR2蛋白表达水平的变化 |
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