戊四氮点燃模型大鼠海马苔藓纤维出芽的动态变化

目的：研究戊四氮（pentylenetetrazole,PTZ）慢性致痫模型点燃前后大鼠海马苔藓纤维出芽的动态变化,以探讨癫痫可能的发病机制。方法：将60只大鼠随机分为对照组和PTZ组（30mg/kg腹腔注射,每天1次）。在点燃前后用Timm染色法观察海马苔藓纤维出芽的动态变化。结果：PTZ组大鼠在行为学和脑电图尚未出现痫性改变之前就有苔藓纤维出芽,且随着点燃效应的逐步建立,苔藓纤维出芽逐渐增强。结论：苔藓纤维出芽可能对癫痫的形成和发展起重要作用。...

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Veröffentlicht in:	Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban 2007, Vol.32 (6), p.1026-1030
1. Verfasser:	田发发郭婷辉陈金梅马云峰蔡小凤姚凤红
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Schlagworte:	点燃癫痫苔藓纤维出芽
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container_title	Zhong nan da xue xue bao. Journal of Central South University. Yi xue ban
container_volume	32
creator	田发发郭婷辉陈金梅马云峰蔡小凤姚凤红
description	目的：研究戊四氮（pentylenetetrazole,PTZ）慢性致痫模型点燃前后大鼠海马苔藓纤维出芽的动态变化,以探讨癫痫可能的发病机制。方法：将60只大鼠随机分为对照组和PTZ组（30mg/kg腹腔注射,每天1次）。在点燃前后用Timm染色法观察海马苔藓纤维出芽的动态变化。结果：PTZ组大鼠在行为学和脑电图尚未出现痫性改变之前就有苔藓纤维出芽,且随着点燃效应的逐步建立,苔藓纤维出芽逐渐增强。结论：苔藓纤维出芽可能对癫痫的形成和发展起重要作用。
doi_str_mv	10.3321/j.issn:1672-7347.2007.06.016
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subjects	点燃癫痫苔藓纤维出芽
title	戊四氮点燃模型大鼠海马苔藓纤维出芽的动态变化
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