Biological evaluation on 125I-ADAM as serotonin transporter ligand

ADAM (2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine) is suggested as a promising serotonin transporter (SERT) imaging agent for central nervous system. In this paper, biodistribution studies in rats showed that the initial uptake of 131I-ADAM in the brain was high (1.087%ID at 2 min po...

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Veröffentlicht in:	Nuclear science and techniques 2007-08, Vol.18 (4), p.218-222
Hauptverfasser:	LEI, Bei, ZHU, Junqing, LU, Chunxiong, JIANG, Quanfu, ZOU, Meifeng, WANG, Songpei, LI, Xiaomin, WU, Chunying
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Biodistribution Depression Imaging agent R749.4 R817 Radionuclide imaging SERT
Online-Zugang:	Volltext
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