Cognitive, Immunologic, Virologic, Functional, and Demographic Predictors of Health-related Quality of Life in People Living with HIV

Background: With recent progress in the treatment of people living with HIV (PLWH) and increasing their survival, quality of life has received highly attention. In the present study, we aimed to investigate the cognitive, immunologic, virologic, functional, and demographic predictors of health-relat...

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Veröffentlicht in:国际转化医学杂志(英文版) 2018-09, Vol.6 (3), p.136-140
Hauptverfasser: Saeed GHODRATI, Zahra SHAHABINEZHAD, SeyedAhmad SEYEDALINAGHI, Nadia SADEGHI, Kazem Baesi, Fabricio VOLTARELLI
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container_issue 3
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container_title 国际转化医学杂志(英文版)
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creator Saeed GHODRATI
Zahra SHAHABINEZHAD
SeyedAhmad SEYEDALINAGHI
Nadia SADEGHI
Kazem Baesi
Fabricio VOLTARELLI
description Background: With recent progress in the treatment of people living with HIV (PLWH) and increasing their survival, quality of life has received highly attention. In the present study, we aimed to investigate the cognitive, immunologic, virologic, functional, and demographic predictors of health-related quality of life in people living with HIV. Methods: The study sample was comprised of 67 HIV-infected individuals who were under treatment of anti-retroviral therapy (ART) in Imam Khomeini Hospital of Iran, Tehran in 2016. We used correlation and step-wise regression to data analysis using SPSS-22 software. Results: The findings of stepwise regression analysis showed that prospective/retrospective memory complaint and daily life functioning were predictors of health-related quality of life in PLWH [P < 0.001, F (2,64) = 18.90, R2 adj = 0.520]. The results also showed that CD4 cell count, viral load, gender, age, and education were not predictors of health-related quality of life in PLWH (P > 0.05). Conclusion: The present article showed that prospective/retrospective memory complaint was a strong predictor of health-related quality of life in PLWH. Daily life functioning was another predictor of health-related quality of life. Considering that people living with HIV live longer with this chronic illness, knowing factors related to HRQoL plays a prominent role in survival and well-being of PLWH.
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In the present study, we aimed to investigate the cognitive, immunologic, virologic, functional, and demographic predictors of health-related quality of life in people living with HIV. Methods: The study sample was comprised of 67 HIV-infected individuals who were under treatment of anti-retroviral therapy (ART) in Imam Khomeini Hospital of Iran, Tehran in 2016. We used correlation and step-wise regression to data analysis using SPSS-22 software. Results: The findings of stepwise regression analysis showed that prospective/retrospective memory complaint and daily life functioning were predictors of health-related quality of life in PLWH [P &lt; 0.001, F (2,64) = 18.90, R2 adj = 0.520]. The results also showed that CD4 cell count, viral load, gender, age, and education were not predictors of health-related quality of life in PLWH (P &gt; 0.05). Conclusion: The present article showed that prospective/retrospective memory complaint was a strong predictor of health-related quality of life in PLWH. Daily life functioning was another predictor of health-related quality of life. Considering that people living with HIV live longer with this chronic illness, knowing factors related to HRQoL plays a prominent role in survival and well-being of PLWH.</description><identifier>ISSN: 2227-6394</identifier><identifier>EISSN: 2227-6394</identifier><identifier>DOI: 10.11910/2227-6394.2018.06.03.06</identifier><language>eng</language><publisher>Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran%Department of Counseling, Kharazmi University, Alborz, Iran%Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran%Department of Psychology, Qazvin Islamic Azad University, Qazvin, Iran%Hepatitis and AIDS Department, Pasture Institute of Iran, Tehran, Iran%Graduation Program of Physical Education, Faculty of Physical Education, Federal University of Mato Grosso, Cuiabá, Brazil</publisher><ispartof>国际转化医学杂志(英文版), 2018-09, Vol.6 (3), p.136-140</ispartof><rights>Copyright © Wanfang Data Co. 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In the present study, we aimed to investigate the cognitive, immunologic, virologic, functional, and demographic predictors of health-related quality of life in people living with HIV. Methods: The study sample was comprised of 67 HIV-infected individuals who were under treatment of anti-retroviral therapy (ART) in Imam Khomeini Hospital of Iran, Tehran in 2016. We used correlation and step-wise regression to data analysis using SPSS-22 software. Results: The findings of stepwise regression analysis showed that prospective/retrospective memory complaint and daily life functioning were predictors of health-related quality of life in PLWH [P &lt; 0.001, F (2,64) = 18.90, R2 adj = 0.520]. The results also showed that CD4 cell count, viral load, gender, age, and education were not predictors of health-related quality of life in PLWH (P &gt; 0.05). Conclusion: The present article showed that prospective/retrospective memory complaint was a strong predictor of health-related quality of life in PLWH. Daily life functioning was another predictor of health-related quality of life. 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In the present study, we aimed to investigate the cognitive, immunologic, virologic, functional, and demographic predictors of health-related quality of life in people living with HIV. Methods: The study sample was comprised of 67 HIV-infected individuals who were under treatment of anti-retroviral therapy (ART) in Imam Khomeini Hospital of Iran, Tehran in 2016. We used correlation and step-wise regression to data analysis using SPSS-22 software. Results: The findings of stepwise regression analysis showed that prospective/retrospective memory complaint and daily life functioning were predictors of health-related quality of life in PLWH [P &lt; 0.001, F (2,64) = 18.90, R2 adj = 0.520]. The results also showed that CD4 cell count, viral load, gender, age, and education were not predictors of health-related quality of life in PLWH (P &gt; 0.05). Conclusion: The present article showed that prospective/retrospective memory complaint was a strong predictor of health-related quality of life in PLWH. Daily life functioning was another predictor of health-related quality of life. 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title Cognitive, Immunologic, Virologic, Functional, and Demographic Predictors of Health-related Quality of Life in People Living with HIV
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