Alendronate and FTI-277 combination as a possible therapeutic approach for hepatocellular carcinoma: An in vitro study

An important product of mevalonate pathway is downstream synthesis of isoprenoid units that has long been implicated in development and progression of tumor. It has been speculated that inhibition of protein prenylation might be therapeutically beneficial. The objective of current study was to evalu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hepatobiliary & pancreatic diseases international 2018-06, Vol.17 (3), p.241-250
Hauptverfasser:	Ilyas, Amber, Hashim, Zehra, Channa, Iffat Saeed, Zarina, Shamshad
Format:	Artikel
Sprache:	eng
Schlagworte:	Alendronate - pharmacology Antineoplastic Combined Chemotherapy Protocols - pharmacology Apoptosis - drug effects Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cell Line, Tumor Chemotherapy Dose-Response Relationship, Drug Electrophoresis, Gel, Two-Dimensional Gene expression Gene Expression Regulation, Neoplastic - drug effects Hepatocellular carcinoma Humans Inhibitory Concentration 50 Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Methionine - analogs & derivatives Methionine - pharmacology Proteomics Proteomics - methods Signal Transduction - drug effects Tandem Mass Spectrometry Therapeutics Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!