Probe Staurosporine Drug Binding Site on Protein Kinase by PFSC

We used a new approach,protein folding shape code（PFSC）,to predict the potential staurosporine binding sites in protein kinases.Firstly,all available three dimensioned（3D） structures of protein kinases in protein databank（PDB） were converted into one-dimensional PFSC description,based on which a PFS...

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Veröffentlicht in:	Chemical research in Chinese universities 2014-08, Vol.30 (4), p.644-649
Hauptverfasser:	Zheng, Kun, Yang, Hong, Zhao, Xiaofei, Jiang, Yang, Sun, Chuantao, Yang, Jia’an
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Physical Chemistry staurosporine 探头 星形 结合位点 结构特征 药物发现 蛋白激酶 蛋白质数据库
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