Synthesis and Evaluation of Nicotinoylamino Acid Compounds as Radiosensitizer

Nicotinoylamino acid compounds 4, 5, 9a, 9b, 9c, 10a and 10b were synthesized with nicotinoyl chloride or nicotinoyl azide as acetylating agents of amino acid esters or amino acids. The compounds were tested for their radiosensitizing activity in Leukemia cell line(L1210) and compared with nicotinam...

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Veröffentlicht in:Chemical research in Chinese universities 2008-07, Vol.24 (4), p.496-500
Hauptverfasser: QIN, Zhi-zhong, ZHANG, Feng-bao, JIANG, Tie-nan, LI, Mei-jia, WANG, Rong-xian, LI, Yi-liang
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Sprache:eng
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