First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament
A novel method for the determination of vitamin C（Vc） is proposed in this article. After the reaction with Folin-Ciocalteau reagent at ambient temperature, Vc solution was scanned at 750--1100 nm, and its first-order derivative spectrum were obtained from the original spectrum. The values of derivat...
Gespeichert in:
| Veröffentlicht in: | Chemical research in Chinese universities 2008, Vol.24 (1), p.29-31 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 31 |
|---|---|
| container_issue | 1 |
| container_start_page | 29 |
| container_title | Chemical research in Chinese universities |
| container_volume | 24 |
| creator | MENG, Qing-fan TENG, Le-sheng JIANG, Chao-jun Jin-shuang, An LI, Lei LU, Jia-hui TENG, Li-rong |
| description | A novel method for the determination of vitamin C（Vc） is proposed in this article. After the reaction with Folin-Ciocalteau reagent at ambient temperature, Vc solution was scanned at 750--1100 nm, and its first-order derivative spectrum were obtained from the original spectrum. The values of derivative selected at 995 nm were used for determination. It was proved that Vc could quickly react with Folin-Ciocalteau reagent within 5 min and the product was quite stable for a long time. The conditions required for this method is not very complicated, its precision and accuracy are similar to those of the iodometric titration described in Chinese Pharmacopoeia, and the limit of detection is 0.312 μg/mL. The determination of the results of vitamin C tablet, pill, and injection demonstrates that this method has wide pharmaceutical applications. |
| doi_str_mv | 10.1016/S1005-9040(08)60007-0 |
| format | Article |
| fullrecord | <record><control><sourceid>wanfang_jour_cross</sourceid><recordid>TN_cdi_wanfang_journals_gdxxhxyj200801007</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>26561732</cqvip_id><wanfj_id>gdxxhxyj200801007</wanfj_id><els_id>S1005904008600070</els_id><sourcerecordid>gdxxhxyj200801007</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-dddad84c99684711f06853faf54d0c016aa76034b86f345af8dc6d941986d8b83</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhoMoWKs_QVg82cPqZLObzZ5EqlWh4qEqeAppPrqp7aZmY23_vekHXr1MGHhmJu-D0DmGKwyYXo8wQJFWkMMlsB4FgDKFA9TJMgwpwSU-RJ0_5BidtO0UgFSU5h30MbC-DanzSvvkTnu7FMEudTJaaBm8W9QuuLkOfp0Y55NQ6wgF7ee2iZxrEmeSdxtE7JN-EsuzVlaKuW7CKToyYtbqs_3bRW-D-9f-Yzp8eXjq3w5TSUoIqVJKKJbLqqIsLzE2QFlBjDBFrkDGeEKUFEg-ZtSQvBCGKUlVleOKUcXGjHRRb7f3RzRGNBM-dd--iRf5RK1W9Wo9zQAYRAFlZIsdK71rW68NX3g7F37NMfCNS751yTeiODC-dckhzt3s5nQMsrTa81Za3cgY1kdPXDn774aL_eXaNZMvG_85FvLT2JnmGS0oLklGfgHFYYdB</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament</title><source>Alma/SFX Local Collection</source><creator>MENG, Qing-fan ; TENG, Le-sheng ; JIANG, Chao-jun ; Jin-shuang, An ; LI, Lei ; LU, Jia-hui ; TENG, Li-rong</creator><creatorcontrib>MENG, Qing-fan ; TENG, Le-sheng ; JIANG, Chao-jun ; Jin-shuang, An ; LI, Lei ; LU, Jia-hui ; TENG, Li-rong</creatorcontrib><description>A novel method for the determination of vitamin C（Vc） is proposed in this article. After the reaction with Folin-Ciocalteau reagent at ambient temperature, Vc solution was scanned at 750--1100 nm, and its first-order derivative spectrum were obtained from the original spectrum. The values of derivative selected at 995 nm were used for determination. It was proved that Vc could quickly react with Folin-Ciocalteau reagent within 5 min and the product was quite stable for a long time. The conditions required for this method is not very complicated, its precision and accuracy are similar to those of the iodometric titration described in Chinese Pharmacopoeia, and the limit of detection is 0.312 μg/mL. The determination of the results of vitamin C tablet, pill, and injection demonstrates that this method has wide pharmaceutical applications.</description><identifier>ISSN: 1005-9040</identifier><identifier>EISSN: 2210-3171</identifier><identifier>DOI: 10.1016/S1005-9040(08)60007-0</identifier><language>eng</language><publisher>Elsevier Ltd</publisher><subject>First-order derivative spectroscopy ; Folin-Ciocalteau regent ; Vitamin C determination ; 分光光度测定法 ; 化学结构 ; 维生素</subject><ispartof>Chemical research in Chinese universities, 2008, Vol.24 (1), p.29-31</ispartof><rights>2008 Jilin University</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-dddad84c99684711f06853faf54d0c016aa76034b86f345af8dc6d941986d8b83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86071X/86071X.jpg</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>MENG, Qing-fan</creatorcontrib><creatorcontrib>TENG, Le-sheng</creatorcontrib><creatorcontrib>JIANG, Chao-jun</creatorcontrib><creatorcontrib>Jin-shuang, An</creatorcontrib><creatorcontrib>LI, Lei</creatorcontrib><creatorcontrib>LU, Jia-hui</creatorcontrib><creatorcontrib>TENG, Li-rong</creatorcontrib><title>First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament</title><title>Chemical research in Chinese universities</title><addtitle>Chemical Research in Chinese University</addtitle><description>A novel method for the determination of vitamin C（Vc） is proposed in this article. After the reaction with Folin-Ciocalteau reagent at ambient temperature, Vc solution was scanned at 750--1100 nm, and its first-order derivative spectrum were obtained from the original spectrum. The values of derivative selected at 995 nm were used for determination. It was proved that Vc could quickly react with Folin-Ciocalteau reagent within 5 min and the product was quite stable for a long time. The conditions required for this method is not very complicated, its precision and accuracy are similar to those of the iodometric titration described in Chinese Pharmacopoeia, and the limit of detection is 0.312 μg/mL. The determination of the results of vitamin C tablet, pill, and injection demonstrates that this method has wide pharmaceutical applications.</description><subject>First-order derivative spectroscopy</subject><subject>Folin-Ciocalteau regent</subject><subject>Vitamin C determination</subject><subject>分光光度测定法</subject><subject>化学结构</subject><subject>维生素</subject><issn>1005-9040</issn><issn>2210-3171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqFkE1LAzEQhoMoWKs_QVg82cPqZLObzZ5EqlWh4qEqeAppPrqp7aZmY23_vekHXr1MGHhmJu-D0DmGKwyYXo8wQJFWkMMlsB4FgDKFA9TJMgwpwSU-RJ0_5BidtO0UgFSU5h30MbC-DanzSvvkTnu7FMEudTJaaBm8W9QuuLkOfp0Y55NQ6wgF7ee2iZxrEmeSdxtE7JN-EsuzVlaKuW7CKToyYtbqs_3bRW-D-9f-Yzp8eXjq3w5TSUoIqVJKKJbLqqIsLzE2QFlBjDBFrkDGeEKUFEg-ZtSQvBCGKUlVleOKUcXGjHRRb7f3RzRGNBM-dd--iRf5RK1W9Wo9zQAYRAFlZIsdK71rW68NX3g7F37NMfCNS751yTeiODC-dckhzt3s5nQMsrTa81Za3cgY1kdPXDn774aL_eXaNZMvG_85FvLT2JnmGS0oLklGfgHFYYdB</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>MENG, Qing-fan</creator><creator>TENG, Le-sheng</creator><creator>JIANG, Chao-jun</creator><creator>Jin-shuang, An</creator><creator>LI, Lei</creator><creator>LU, Jia-hui</creator><creator>TENG, Li-rong</creator><general>Elsevier Ltd</general><general>College of Life Science,Jilin University,Changchun 130012,P.R.China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>2008</creationdate><title>First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament</title><author>MENG, Qing-fan ; TENG, Le-sheng ; JIANG, Chao-jun ; Jin-shuang, An ; LI, Lei ; LU, Jia-hui ; TENG, Li-rong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-dddad84c99684711f06853faf54d0c016aa76034b86f345af8dc6d941986d8b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>First-order derivative spectroscopy</topic><topic>Folin-Ciocalteau regent</topic><topic>Vitamin C determination</topic><topic>分光光度测定法</topic><topic>化学结构</topic><topic>维生素</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MENG, Qing-fan</creatorcontrib><creatorcontrib>TENG, Le-sheng</creatorcontrib><creatorcontrib>JIANG, Chao-jun</creatorcontrib><creatorcontrib>Jin-shuang, An</creatorcontrib><creatorcontrib>LI, Lei</creatorcontrib><creatorcontrib>LU, Jia-hui</creatorcontrib><creatorcontrib>TENG, Li-rong</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>CrossRef</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chemical research in Chinese universities</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MENG, Qing-fan</au><au>TENG, Le-sheng</au><au>JIANG, Chao-jun</au><au>Jin-shuang, An</au><au>LI, Lei</au><au>LU, Jia-hui</au><au>TENG, Li-rong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament</atitle><jtitle>Chemical research in Chinese universities</jtitle><addtitle>Chemical Research in Chinese University</addtitle><date>2008</date><risdate>2008</risdate><volume>24</volume><issue>1</issue><spage>29</spage><epage>31</epage><pages>29-31</pages><issn>1005-9040</issn><eissn>2210-3171</eissn><abstract>A novel method for the determination of vitamin C（Vc） is proposed in this article. After the reaction with Folin-Ciocalteau reagent at ambient temperature, Vc solution was scanned at 750--1100 nm, and its first-order derivative spectrum were obtained from the original spectrum. The values of derivative selected at 995 nm were used for determination. It was proved that Vc could quickly react with Folin-Ciocalteau reagent within 5 min and the product was quite stable for a long time. The conditions required for this method is not very complicated, its precision and accuracy are similar to those of the iodometric titration described in Chinese Pharmacopoeia, and the limit of detection is 0.312 μg/mL. The determination of the results of vitamin C tablet, pill, and injection demonstrates that this method has wide pharmaceutical applications.</abstract><pub>Elsevier Ltd</pub><doi>10.1016/S1005-9040(08)60007-0</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1005-9040 |
| ispartof | Chemical research in Chinese universities, 2008, Vol.24 (1), p.29-31 |
| issn | 1005-9040 2210-3171 |
| language | eng |
| recordid | cdi_wanfang_journals_gdxxhxyj200801007 |
| source | Alma/SFX Local Collection |
| subjects | First-order derivative spectroscopy Folin-Ciocalteau regent Vitamin C determination 分光光度测定法 化学结构 维生素 |
| title | First-order Derivative Spectrophotometry for the Determination of Vitamin C in Medicament |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T00%3A08%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wanfang_jour_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=First-order%20Derivative%20Spectrophotometry%20for%20the%20Determination%20of%20Vitamin%20C%20in%20Medicament&rft.jtitle=Chemical%20research%20in%20Chinese%20universities&rft.au=MENG,%20Qing-fan&rft.date=2008&rft.volume=24&rft.issue=1&rft.spage=29&rft.epage=31&rft.pages=29-31&rft.issn=1005-9040&rft.eissn=2210-3171&rft_id=info:doi/10.1016/S1005-9040(08)60007-0&rft_dat=%3Cwanfang_jour_cross%3Egdxxhxyj200801007%3C/wanfang_jour_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=26561732&rft_wanfj_id=gdxxhxyj200801007&rft_els_id=S1005904008600070&rfr_iscdi=true |