Application of ^18F-fluorodeoxyglucose Positron Emission Tomography in Diagnosis of Malignant Diseases
Objective To testify the efficacy of ^18F-fluorodeoxyglucose （^18F-FDG） positron emission tomography （PET） in the diagnosis of cancer. Methods A total of 170 patients with diagnosed cancer or suspicious cancer were enrolled in this study, and underwent ^18F-FDG PET. The standard uptake value （SUV） a...
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| Veröffentlicht in: | Chinese medical sciences journal 2009-06, Vol.24 (2), p.117-121 |
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| creator | Ning, Xiao-hong Meng, Qiu-li Wang, Yu-zhou Bai, Chun-mei |
| description | Objective To testify the efficacy of ^18F-fluorodeoxyglucose （^18F-FDG） positron emission tomography （PET） in the diagnosis of cancer. Methods A total of 170 patients with diagnosed cancer or suspicious cancer were enrolled in this study, and underwent ^18F-FDG PET. The standard uptake value （SUV） and diameter for each abnormal region in PET images were analyzed. All data were analyzed by SPSS 11.5. Results PET scan identified a primary cancer in 45.8% （11/24） patients. The sensitivity and specificity of PET scan in differentiating malignant lesions from benign ones were 78.8% （52/66） and 77.1% （27/35） respectively. Twenty-nine out of 68 （42.6%） lesions were detected earlier by PET than by computed tomography. The SHV of primary cancer was significantly higher than that of metastatic lymph nodes （5.84± 3.12 vs. 3.14± 2.24, P〈0.001）. And SLIV of primary lung cancer was also significantly higher than that of metastatic lung cancer （6.30±3.01 vs. 2.86±2.37, P〈0.01）.Conclusion ^18F-FDG PET plays a very important role in cancer diagnosis. |
| doi_str_mv | 10.1016/S1001-9294(09)60073-0 |
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Methods A total of 170 patients with diagnosed cancer or suspicious cancer were enrolled in this study, and underwent ^18F-FDG PET. The standard uptake value （SUV） and diameter for each abnormal region in PET images were analyzed. All data were analyzed by SPSS 11.5. Results PET scan identified a primary cancer in 45.8% （11/24） patients. The sensitivity and specificity of PET scan in differentiating malignant lesions from benign ones were 78.8% （52/66） and 77.1% （27/35） respectively. Twenty-nine out of 68 （42.6%） lesions were detected earlier by PET than by computed tomography. The SHV of primary cancer was significantly higher than that of metastatic lymph nodes （5.84± 3.12 vs. 3.14± 2.24, P〈0.001）. And SLIV of primary lung cancer was also significantly higher than that of metastatic lung cancer （6.30±3.01 vs. 2.86±2.37, P〈0.01）.Conclusion ^18F-FDG PET plays a very important role in cancer diagnosis.</description><identifier>ISSN: 1001-9294</identifier><identifier>DOI: 10.1016/S1001-9294(09)60073-0</identifier><identifier>PMID: 19618610</identifier><language>eng</language><publisher>China: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; diagnosis ; Female ; Fluorodeoxyglucose F18 ; Humans ; Male ; malignant cancer ; Middle Aged ; Neoplasm Metastasis ; Neoplasms - diagnosis ; Neoplasms - pathology ; Neoplasms, Unknown Primary - diagnosis ; Neoplasms, Unknown Primary - pathology ; positron emission tomography ; Positron-Emission Tomography - methods ; Radiopharmaceuticals - metabolism ; Retrospective Studies ; Sensitivity and Specificity ; Young Adult ; 正电子发射 ; 计算机断层扫描</subject><ispartof>Chinese medical sciences journal, 2009-06, Vol.24 (2), p.117-121</ispartof><rights>2009 Chinese Academy Medical Sciences</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2670-eb3d00762d54dba4827ea594e7f7ee93d76ae7f1f1eb1368fea953294661dce73</citedby><cites>FETCH-LOGICAL-c2670-eb3d00762d54dba4827ea594e7f7ee93d76ae7f1f1eb1368fea953294661dce73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86798X/86798X.jpg</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19618610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ning, Xiao-hong</creatorcontrib><creatorcontrib>Meng, Qiu-li</creatorcontrib><creatorcontrib>Wang, Yu-zhou</creatorcontrib><creatorcontrib>Bai, Chun-mei</creatorcontrib><title>Application of ^18F-fluorodeoxyglucose Positron Emission Tomography in Diagnosis of Malignant Diseases</title><title>Chinese medical sciences journal</title><addtitle>Chinese Medical Sciences Journal</addtitle><description>Objective To testify the efficacy of ^18F-fluorodeoxyglucose （^18F-FDG） positron emission tomography （PET） in the diagnosis of cancer. Methods A total of 170 patients with diagnosed cancer or suspicious cancer were enrolled in this study, and underwent ^18F-FDG PET. The standard uptake value （SUV） and diameter for each abnormal region in PET images were analyzed. All data were analyzed by SPSS 11.5. Results PET scan identified a primary cancer in 45.8% （11/24） patients. The sensitivity and specificity of PET scan in differentiating malignant lesions from benign ones were 78.8% （52/66） and 77.1% （27/35） respectively. Twenty-nine out of 68 （42.6%） lesions were detected earlier by PET than by computed tomography. The SHV of primary cancer was significantly higher than that of metastatic lymph nodes （5.84± 3.12 vs. 3.14± 2.24, P〈0.001）. And SLIV of primary lung cancer was also significantly higher than that of metastatic lung cancer （6.30±3.01 vs. 2.86±2.37, P〈0.01）.Conclusion ^18F-FDG PET plays a very important role in cancer diagnosis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>diagnosis</subject><subject>Female</subject><subject>Fluorodeoxyglucose F18</subject><subject>Humans</subject><subject>Male</subject><subject>malignant cancer</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis</subject><subject>Neoplasms - diagnosis</subject><subject>Neoplasms - pathology</subject><subject>Neoplasms, Unknown Primary - diagnosis</subject><subject>Neoplasms, Unknown Primary - pathology</subject><subject>positron emission tomography</subject><subject>Positron-Emission Tomography - methods</subject><subject>Radiopharmaceuticals - metabolism</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Young Adult</subject><subject>正电子发射</subject><subject>计算机断层扫描</subject><issn>1001-9294</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1TAQhb0A0VL4CaCIBdBFyjgPJ16hqvSBVAQSZYvl2OPUl8RO7QS4_75O7xUsu5rR6Js5cw4hryicUKDsw3cKQHNe8Oo98GMG0JQ5PCGH_8YH5HmMGwBgtK2ekQPKU8MoHBJzOk2DVXK23mXeZD9pe5GbYfHBa_R_t_2wKB8x--ajnUNizkcb4wrf-NH3QU6328y67JOVvUtMXI98kYPtnXRzGkeUEeML8tTIIeLLfT0iPy7Ob86u8uuvl5_PTq9zVbAGcuxKnb5nha4r3cmqLRqUNa-wMQ0iL3XDZOqpodjRkrUGJa_LZJAxqhU25RF5t7v7RzojXS82fgkuKQo1xo3AAoBDARQS-XZHTsHfLRhnkYwpHAbp0C9RsKYGyusVrHegCj7GgEZMwY4ybAUFscYvHuIXa84CuHiIX6x7r_cCSzei_r-1zz4BH3cApkB-WwwiKotOobYB1Sy0t49KvNm_dutdf2eT306qX8YOKEpoq7amVXkPMleimA</recordid><startdate>200906</startdate><enddate>200906</enddate><creator>Ning, Xiao-hong</creator><creator>Meng, Qiu-li</creator><creator>Wang, Yu-zhou</creator><creator>Bai, Chun-mei</creator><general>Elsevier B.V</general><general>Department of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China%Department of Medical Oncology, Gongyi Renmin Hospital, Gongyi 451200, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W92</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>200906</creationdate><title>Application of ^18F-fluorodeoxyglucose Positron Emission Tomography in Diagnosis of Malignant Diseases</title><author>Ning, Xiao-hong ; Meng, Qiu-li ; Wang, Yu-zhou ; Bai, Chun-mei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2670-eb3d00762d54dba4827ea594e7f7ee93d76ae7f1f1eb1368fea953294661dce73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>diagnosis</topic><topic>Female</topic><topic>Fluorodeoxyglucose F18</topic><topic>Humans</topic><topic>Male</topic><topic>malignant cancer</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis</topic><topic>Neoplasms - diagnosis</topic><topic>Neoplasms - pathology</topic><topic>Neoplasms, Unknown Primary - diagnosis</topic><topic>Neoplasms, Unknown Primary - pathology</topic><topic>positron emission tomography</topic><topic>Positron-Emission Tomography - methods</topic><topic>Radiopharmaceuticals - metabolism</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Young Adult</topic><topic>正电子发射</topic><topic>计算机断层扫描</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ning, Xiao-hong</creatorcontrib><creatorcontrib>Meng, Qiu-li</creatorcontrib><creatorcontrib>Wang, Yu-zhou</creatorcontrib><creatorcontrib>Bai, Chun-mei</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-工程技术</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese medical sciences journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ning, Xiao-hong</au><au>Meng, Qiu-li</au><au>Wang, Yu-zhou</au><au>Bai, Chun-mei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application of ^18F-fluorodeoxyglucose Positron Emission Tomography in Diagnosis of Malignant Diseases</atitle><jtitle>Chinese medical sciences journal</jtitle><addtitle>Chinese Medical Sciences Journal</addtitle><date>2009-06</date><risdate>2009</risdate><volume>24</volume><issue>2</issue><spage>117</spage><epage>121</epage><pages>117-121</pages><issn>1001-9294</issn><abstract>Objective To testify the efficacy of ^18F-fluorodeoxyglucose （^18F-FDG） positron emission tomography （PET） in the diagnosis of cancer. Methods A total of 170 patients with diagnosed cancer or suspicious cancer were enrolled in this study, and underwent ^18F-FDG PET. The standard uptake value （SUV） and diameter for each abnormal region in PET images were analyzed. All data were analyzed by SPSS 11.5. Results PET scan identified a primary cancer in 45.8% （11/24） patients. The sensitivity and specificity of PET scan in differentiating malignant lesions from benign ones were 78.8% （52/66） and 77.1% （27/35） respectively. Twenty-nine out of 68 （42.6%） lesions were detected earlier by PET than by computed tomography. The SHV of primary cancer was significantly higher than that of metastatic lymph nodes （5.84± 3.12 vs. 3.14± 2.24, P〈0.001）. And SLIV of primary lung cancer was also significantly higher than that of metastatic lung cancer （6.30±3.01 vs. 2.86±2.37, P〈0.01）.Conclusion ^18F-FDG PET plays a very important role in cancer diagnosis.</abstract><cop>China</cop><pub>Elsevier B.V</pub><pmid>19618610</pmid><doi>10.1016/S1001-9294(09)60073-0</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Aged, 80 and over diagnosis Female Fluorodeoxyglucose F18 Humans Male malignant cancer Middle Aged Neoplasm Metastasis Neoplasms - diagnosis Neoplasms - pathology Neoplasms, Unknown Primary - diagnosis Neoplasms, Unknown Primary - pathology positron emission tomography Positron-Emission Tomography - methods Radiopharmaceuticals - metabolism Retrospective Studies Sensitivity and Specificity Young Adult 正电子发射 计算机断层扫描 |
| title | Application of ^18F-fluorodeoxyglucose Positron Emission Tomography in Diagnosis of Malignant Diseases |
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