IGF-1 Accelerates Cell Aging by Inhibiting POLD1 Expression

ObjectiveThe individual cascades of the insulin-like growth factor-1 (IGF-1) signaling pathway and the molecular mechanism of aging have not been fully clarified. In the current study, we explored the effect of DNA polymerase delta 1 (POLD1) on the IGF-1 signaling pathway in cell aging. MethodsFirst...

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Veröffentlicht in:Biomedical and environmental sciences 2022-11, Vol.35 (11), p.981-991
Hauptverfasser: Hou, Yu Li, Wang, Yi Fei, Song, Qiao, Zhang, Xiao Min, Liu, Jing, Wang, Ya Qi, Cui, Yu Ting, Fu, Jing Xuan, Feng, Zi Yi, Zhang, Chi, Wang, Pei Chang
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Sprache:eng
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