Dietary Exposure to Benzyl Butyl Phthalate in China
Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents...
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| Veröffentlicht in: | Biomedical and environmental sciences 2016-05, Vol.29 (5), p.365-373 |
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| creator | ZHANG, Lei JIANG, Ding Guo SUI, Hai Xia WU, Ping Gu LIU, Ai Dong YANG, Da Jin LIU, Zhao Ping SONG, Yan LI, Ning |
| description | Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern. |
| doi_str_mv | 10.3967/bes2016.047 |
| format | Article |
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Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.</description><identifier>ISSN: 0895-3988</identifier><identifier>EISSN: 2214-0190</identifier><identifier>DOI: 10.3967/bes2016.047</identifier><identifier>PMID: 27353711</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Benzyl butyl phthalate ; Child ; Child, Preschool ; China ; Diet ; Dietary exposure ; Environmental Exposure ; Environmental Pollutants - analysis ; Female ; Food Contamination - analysis ; Food Packaging ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Middle Aged ; Phthalic Acids - analysis ; Plasticizers - analysis ; Risk assessment ; Young Adult ; 中国人群 ; 样品检测 ; 气相色谱-质谱法 ; 甲酸苄酯 ; 膳食 ; 选择离子监测 ; 邻苯二甲酸酯 ; 食品接触材料</subject><ispartof>Biomedical and environmental sciences, 2016-05, Vol.29 (5), p.365-373</ispartof><rights>2016 The Editorial Board of Biomedical and Environmental Sciences</rights><rights>Copyright © 2016 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84046X/84046X.jpg</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0895398816300605$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27353711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ZHANG, Lei</creatorcontrib><creatorcontrib>JIANG, Ding Guo</creatorcontrib><creatorcontrib>SUI, Hai Xia</creatorcontrib><creatorcontrib>WU, Ping Gu</creatorcontrib><creatorcontrib>LIU, Ai Dong</creatorcontrib><creatorcontrib>YANG, Da Jin</creatorcontrib><creatorcontrib>LIU, Zhao Ping</creatorcontrib><creatorcontrib>SONG, Yan</creatorcontrib><creatorcontrib>LI, Ning</creatorcontrib><title>Dietary Exposure to Benzyl Butyl Phthalate in China</title><title>Biomedical and environmental sciences</title><addtitle>Biomedical and Environmental Sciences</addtitle><description>Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Benzyl butyl phthalate</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>China</subject><subject>Diet</subject><subject>Dietary exposure</subject><subject>Environmental Exposure</subject><subject>Environmental Pollutants - analysis</subject><subject>Female</subject><subject>Food Contamination - analysis</subject><subject>Food Packaging</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Phthalic Acids - analysis</subject><subject>Plasticizers - analysis</subject><subject>Risk assessment</subject><subject>Young Adult</subject><subject>中国人群</subject><subject>样品检测</subject><subject>气相色谱-质谱法</subject><subject>甲酸苄酯</subject><subject>膳食</subject><subject>选择离子监测</subject><subject>邻苯二甲酸酯</subject><subject>食品接触材料</subject><issn>0895-3988</issn><issn>2214-0190</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kL1PwzAQxS0EoqUwsaMIMbCk-OJ82CMt5UOqBAPMluNcGlepU-IEKH89RmmXu-X37t57hFwCnTKRZnc5uohCOqVxdkTGUQRxSEHQYzKmXCQhE5yPyJlza0pjEDE_JaMoYwnLAMaEPRjsVLsLFj_bxvUtBl0TzND-7upg1nd-vlVdpWrVYWBsMK-MVefkpFS1w4v9npCPx8X7_Dlcvj69zO-XoWbAulADRcFyJnIokCcINMujIo9VEXGtuShTxIxhAjkqXioeRxoEAGRYlAo0sAm5Ge5-K1squ5Lrpm-t_yj3kWlCaeax2wHbts1nj66TG-M01rWy2PROAveUb4QLj17t0T7fYCG3rdn48PLQhweSAUCf68tgK502aDUWpkXdyaIxEqj87_1gQvreve560OmqsatP480ebqep8E7jlLM_bg19LQ</recordid><startdate>20160501</startdate><enddate>20160501</enddate><creator>ZHANG, Lei</creator><creator>JIANG, Ding Guo</creator><creator>SUI, Hai Xia</creator><creator>WU, Ping Gu</creator><creator>LIU, Ai Dong</creator><creator>YANG, Da Jin</creator><creator>LIU, Zhao Ping</creator><creator>SONG, Yan</creator><creator>LI, Ning</creator><general>Elsevier B.V</general><general>Key Laboratory of Food Safety Risk Assessment, NationalHealth and Family Planning Commission of the People’s Republic of China China National Center for Food Safety Risk Assessment, Beijing 100022, China%Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20160501</creationdate><title>Dietary Exposure to Benzyl Butyl Phthalate in China</title><author>ZHANG, Lei ; JIANG, Ding Guo ; SUI, Hai Xia ; WU, Ping Gu ; LIU, Ai Dong ; YANG, Da Jin ; LIU, Zhao Ping ; SONG, Yan ; LI, Ning</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-c10e93b39b1de85e107b2db4ad28cc89f6ee73e51bea8fa842c191117edfa1c13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Benzyl butyl phthalate</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>China</topic><topic>Diet</topic><topic>Dietary exposure</topic><topic>Environmental Exposure</topic><topic>Environmental Pollutants - analysis</topic><topic>Female</topic><topic>Food Contamination - analysis</topic><topic>Food Packaging</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Phthalic Acids - analysis</topic><topic>Plasticizers - analysis</topic><topic>Risk assessment</topic><topic>Young Adult</topic><topic>中国人群</topic><topic>样品检测</topic><topic>气相色谱-质谱法</topic><topic>甲酸苄酯</topic><topic>膳食</topic><topic>选择离子监测</topic><topic>邻苯二甲酸酯</topic><topic>食品接触材料</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ZHANG, Lei</creatorcontrib><creatorcontrib>JIANG, Ding Guo</creatorcontrib><creatorcontrib>SUI, Hai Xia</creatorcontrib><creatorcontrib>WU, Ping Gu</creatorcontrib><creatorcontrib>LIU, Ai Dong</creatorcontrib><creatorcontrib>YANG, Da Jin</creatorcontrib><creatorcontrib>LIU, Zhao Ping</creatorcontrib><creatorcontrib>SONG, Yan</creatorcontrib><creatorcontrib>LI, Ning</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Biomedical and environmental sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZHANG, Lei</au><au>JIANG, Ding Guo</au><au>SUI, Hai Xia</au><au>WU, Ping Gu</au><au>LIU, Ai Dong</au><au>YANG, Da Jin</au><au>LIU, Zhao Ping</au><au>SONG, Yan</au><au>LI, Ning</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary Exposure to Benzyl Butyl Phthalate in China</atitle><jtitle>Biomedical and environmental sciences</jtitle><addtitle>Biomedical and Environmental Sciences</addtitle><date>2016-05-01</date><risdate>2016</risdate><volume>29</volume><issue>5</issue><spage>365</spage><epage>373</epage><pages>365-373</pages><issn>0895-3988</issn><eissn>2214-0190</eissn><abstract>Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>27353711</pmid><doi>10.3967/bes2016.047</doi><tpages>9</tpages></addata></record> |
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| ispartof | Biomedical and environmental sciences, 2016-05, Vol.29 (5), p.365-373 |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Aged, 80 and over Benzyl butyl phthalate Child Child, Preschool China Diet Dietary exposure Environmental Exposure Environmental Pollutants - analysis Female Food Contamination - analysis Food Packaging Gas Chromatography-Mass Spectrometry Humans Male Middle Aged Phthalic Acids - analysis Plasticizers - analysis Risk assessment Young Adult 中国人群 样品检测 气相色谱-质谱法 甲酸苄酯 膳食 选择离子监测 邻苯二甲酸酯 食品接触材料 |
| title | Dietary Exposure to Benzyl Butyl Phthalate in China |
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