Central Obesity and Metabolic Risk Factors in Middle-aged Chinese
Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged C...
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description | Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors. |
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Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.</description><identifier>ISSN: 0895-3988</identifier><identifier>EISSN: 2214-0190</identifier><identifier>DOI: 10.3967/bes2014.059</identifier><identifier>PMID: 24827715</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Aged ; Central obesity ; Central pre-obesity ; China - epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Intra-Abdominal Fat - physiopathology ; Male ; Metabolic syndrome ; Metabolic Syndrome - diagnosis ; Metabolic Syndrome - epidemiology ; Metabolic Syndrome - physiopathology ; Middle Aged ; Middle-aged Chinese ; Obesity - diagnosis ; ROC Curve ; Waist Circumference ; 中国 ; 中央 ; 中年 ; 临界值 ; 代谢综合征 ; 危险因素 ; 组成部分 ; 肥胖</subject><ispartof>Biomedical and environmental sciences, 2014-05, Vol.27 (5), p.343-352</ispartof><rights>2014 The Editorial Board of Biomedical and Environmental Sciences</rights><rights>Copyright © 2014 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-8fcb6f96ed2b2119cf53ebd0af0325d4d35e8a0af9759a7cb49ca9c91ff738513</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84046X/84046X.jpg</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0895398814600532$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24827715$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>YIN, Xue Yao</creatorcontrib><creatorcontrib>ZHENG, Fen Ping</creatorcontrib><creatorcontrib>ZHOU, Jia Qiang</creatorcontrib><creatorcontrib>DU, Ying</creatorcontrib><creatorcontrib>PAN, Qian Qian</creatorcontrib><creatorcontrib>ZHANG, Sai Fei</creatorcontrib><creatorcontrib>YU, Dan</creatorcontrib><creatorcontrib>LI, Hong</creatorcontrib><title>Central Obesity and Metabolic Risk Factors in Middle-aged Chinese</title><title>Biomedical and environmental sciences</title><addtitle>Biomedical and Environmental Sciences</addtitle><description>Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.</description><subject>Aged</subject><subject>Central obesity</subject><subject>Central pre-obesity</subject><subject>China - epidemiology</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Intra-Abdominal Fat - physiopathology</subject><subject>Male</subject><subject>Metabolic syndrome</subject><subject>Metabolic Syndrome - diagnosis</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Metabolic Syndrome - physiopathology</subject><subject>Middle Aged</subject><subject>Middle-aged Chinese</subject><subject>Obesity - diagnosis</subject><subject>ROC Curve</subject><subject>Waist Circumference</subject><subject>中国</subject><subject>中央</subject><subject>中年</subject><subject>临界值</subject><subject>代谢综合征</subject><subject>危险因素</subject><subject>组成部分</subject><subject>肥胖</subject><issn>0895-3988</issn><issn>2214-0190</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kctLxDAQxoMo7vo4eZcKHrx0zbNNjlJ8gbIgeg5pMl2zdlNtWsX_3kh3T8PAb775vhmEzgheMFWU1zVEiglfYKH20JxSwnNMFN5HcyyVyJmScoaOYlxjzIni8hDNKJe0LImYo5sKwtCbNlsmGT_8Zia47BkGU3ett9mLjx_ZnbFD18fMh-zZO9dCblbgsurdB4hwgg4a00Y43dZj9HZ3-1o95E_L-8fq5im3TPAhl42ti0YV4GhNCVG2EQxqh02DGRWOOyZAmtSqUihT2pora5RVpGlKJgVhx-hy0v0xoTFhpdfd2Ie0UW8PgEUKmLCrCfvsu68R4qA3PlpoWxOgG6MmgoqyEAUVCT3fomO9Aac_e78x_a_eXScBYgIg5fr20OtoPQQLzvdgB-06rwnW_1_YmdDpC2nuYpqz711YfflkdqfNVSFxqTD7A5QogbM</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>YIN, Xue Yao</creator><creator>ZHENG, Fen Ping</creator><creator>ZHOU, Jia Qiang</creator><creator>DU, Ying</creator><creator>PAN, Qian Qian</creator><creator>ZHANG, Sai Fei</creator><creator>YU, Dan</creator><creator>LI, Hong</creator><general>Elsevier B.V</general><general>Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20140501</creationdate><title>Central Obesity and Metabolic Risk Factors in Middle-aged Chinese</title><author>YIN, Xue Yao ; ZHENG, Fen Ping ; ZHOU, Jia Qiang ; DU, Ying ; PAN, Qian Qian ; ZHANG, Sai Fei ; YU, Dan ; LI, Hong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-8fcb6f96ed2b2119cf53ebd0af0325d4d35e8a0af9759a7cb49ca9c91ff738513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Central obesity</topic><topic>Central pre-obesity</topic><topic>China - epidemiology</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Intra-Abdominal Fat - physiopathology</topic><topic>Male</topic><topic>Metabolic syndrome</topic><topic>Metabolic Syndrome - diagnosis</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Metabolic Syndrome - physiopathology</topic><topic>Middle Aged</topic><topic>Middle-aged Chinese</topic><topic>Obesity - diagnosis</topic><topic>ROC Curve</topic><topic>Waist Circumference</topic><topic>中国</topic><topic>中央</topic><topic>中年</topic><topic>临界值</topic><topic>代谢综合征</topic><topic>危险因素</topic><topic>组成部分</topic><topic>肥胖</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YIN, Xue Yao</creatorcontrib><creatorcontrib>ZHENG, Fen Ping</creatorcontrib><creatorcontrib>ZHOU, Jia Qiang</creatorcontrib><creatorcontrib>DU, Ying</creatorcontrib><creatorcontrib>PAN, Qian Qian</creatorcontrib><creatorcontrib>ZHANG, Sai Fei</creatorcontrib><creatorcontrib>YU, Dan</creatorcontrib><creatorcontrib>LI, Hong</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Biomedical and environmental sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YIN, Xue Yao</au><au>ZHENG, Fen Ping</au><au>ZHOU, Jia Qiang</au><au>DU, Ying</au><au>PAN, Qian Qian</au><au>ZHANG, Sai Fei</au><au>YU, Dan</au><au>LI, Hong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Obesity and Metabolic Risk Factors in Middle-aged Chinese</atitle><jtitle>Biomedical and environmental sciences</jtitle><addtitle>Biomedical and Environmental Sciences</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>27</volume><issue>5</issue><spage>343</spage><epage>352</epage><pages>343-352</pages><issn>0895-3988</issn><eissn>2214-0190</eissn><abstract>Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>24827715</pmid><doi>10.3967/bes2014.059</doi><tpages>10</tpages></addata></record> |
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subjects | Aged Central obesity Central pre-obesity China - epidemiology Cross-Sectional Studies Female Humans Intra-Abdominal Fat - physiopathology Male Metabolic syndrome Metabolic Syndrome - diagnosis Metabolic Syndrome - epidemiology Metabolic Syndrome - physiopathology Middle Aged Middle-aged Chinese Obesity - diagnosis ROC Curve Waist Circumference 中国 中央 中年 临界值 代谢综合征 危险因素 组成部分 肥胖 |
title | Central Obesity and Metabolic Risk Factors in Middle-aged Chinese |
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